biostudies-literatureUnknown11Yang Y<i>Mycogone perniciosa</i> causes wet bubble disease in <i>Agaricus bisporus</i> and various Agaricomycetes species. In a previous work, we identified 41 GH18 chitinase genes and other pathogenicity-related genes in the genome of <i>M</i>. <i>perniciosa</i> Hp10. Chitinases are enzymes that degrade chitin, and they have diverse functions in nutrition, morphogenesis, and pathogenesis. However, these important genes in <i>M</i>. <i>perniciosa</i> have not been fully characterized, and their functions remain unclear. Here, we performed a genome-wide analysis of <i>M</i>. <i>perniciosa</i> GH18 genes and analyzed the transcriptome profiles and GH18 expression patterns in <i>M</i>. <i>perniciosa</i> during the time course of infection in <i>A</i>. <i>bisporus</i>. Phylogenetic analysis of the 4Frontiers in microbiology596719https://www.ebi.ac.uk/biostudies/studies/S-EPMC7829358biostudies-literatureGenome-Wide Identification and Analysis of Chitinase GH18 Gene Family in <i>Mycogone perniciosa</i>.PMC7829358Sossah FLLi YYang YLi ZLi DFu YYuan XHyde KDXiao SfalseGenome-Wide Identification and Analysis of Chitinase GH18 Gene Family in <i>Mycogone perniciosa</i>.<i>Mycogone perniciosa</i> causes wet bubble disease in <i>Agaricus bisporus</i> and various Agaricomycetes species. In a previous work, we identified 41 GH18 chitinase genes and other pathogenicity-related genes in the genome of <i>M</i>. <i>perniciosa</i> Hp10. Chitinases are enzymes that degrade chitin, and they have diverse functions in nutrition, morphogenesis, and pathogenesis. However, these important genes in <i>M</i>. <i>perniciosa</i> have not been fully characterized, and their functions remain unclear. Here, we performed a genome-wide analysis of <i>M</i>. <i>perniciosa</i> GH18 genes and analyzed the transcriptome profiles and GH18 expression patterns in <i>M</i>. <i>perniciosa</i> during the time course of infection in <i>A</i>. <i>bisporus</i>. Phylogenetic analysis of the 42020-01-01T00:00:00Z20202025-04-26T05:14:21.387Z2021-02-21T03:40:05ZS-EPMC78293583350536810.3389/fmicb.2020.596719