{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhu Z"],"funding":["National Natural Science Foundation of China"],"pagination":["603513"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7835968"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8"],"pubmed_abstract":["The stressed cultivations are widely used in microalgae R&D for the biofuel production with the repress on growth to a certain degree, which limits the overall productivity. The balance between the growth and energy storage compounds accumulation is a target needing the combination of both strain selection or construction and culture optimization. Here, an engineered strain of <i>Chlamydomonas reinhardtii</i>, in which the chloroplast type glyceraldehyde-3-phosphate dehydrogenase (cGAPDH) was overexpressed and named as P3-GAPDH, was cultured on the Algal Station platform. Compared with wild type (WT), <i>C. reinhardtii</i> CC137c, in Tris-acetate-phosphate (TAP) medium, the highest density of WT and P3-GAPDH were 1.23 ± 0.13 and 1.74 ± 0.09 g L<sup>-1</sup> within 96 h, and the maximum bio"],"journal":["Frontiers in bioengineering and biotechnology"],"pubmed_title":["A Carbon Fixation Enhanced <i>Chlamydomonas reinhardtii</i> Strain for Achieving the Double-Win Between Growth and Biofuel Production Under Non-stressed Conditions."],"pmcid":["PMC7835968"],"funding_grant_id":["21878285","31771914"],"pubmed_authors":["Tian J","Li X","Zhu Z","Cao H","Cao X","Rong J"],"additional_accession":[]},"is_claimable":false,"name":"A Carbon Fixation Enhanced <i>Chlamydomonas reinhardtii</i> Strain for Achieving the Double-Win Between Growth and Biofuel Production Under Non-stressed Conditions.","description":"The stressed cultivations are widely used in microalgae R&D for the biofuel production with the repress on growth to a certain degree, which limits the overall productivity. The balance between the growth and energy storage compounds accumulation is a target needing the combination of both strain selection or construction and culture optimization. Here, an engineered strain of <i>Chlamydomonas reinhardtii</i>, in which the chloroplast type glyceraldehyde-3-phosphate dehydrogenase (cGAPDH) was overexpressed and named as P3-GAPDH, was cultured on the Algal Station platform. Compared with wild type (WT), <i>C. reinhardtii</i> CC137c, in Tris-acetate-phosphate (TAP) medium, the highest density of WT and P3-GAPDH were 1.23 ± 0.13 and 1.74 ± 0.09 g L<sup>-1</sup> within 96 h, and the maximum bio","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2025-04-18T20:44:12.075Z","creation":"2021-02-21T04:33:58Z"},"accession":"S-EPMC7835968","cross_references":{"pubmed":["33511104"],"doi":["10.3389/fbioe.2020.603513"]}}