{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11"],"submitter":["Liu XL"],"pubmed_abstract":["<i>Yellow</i> genes are thought to be involved in the melanin biosynthetic pathway and play a crucial role in pigmentation reactions in insects. However, little research has been done on <i>yellow</i> genes in lepidopteran pests. To clarify the function of one of the <i>yellow</i> genes (<i>yellow-y</i>) in <i>Spodoptera litura</i>, we cloned the full-length of <i>yellow-y</i>, and investigated its spatial and temporal expression profiles by quantitative real-time PCR (qPCR). It revealed that <i>yellow-y</i> was highly expressed in larva of fourth, fifth, and sixth instars, as well as in epidermis (Ep), fat bodies (FB), Malpighian tubes (MT), and midguts (MG) of the larvae; whereas it was expressed in very low levels in different tissues of adults, and was almost undetected in pupa. This e"],"journal":["Frontiers in physiology"],"pagination":["615391"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7839173"],"repository":["biostudies-literature"],"pubmed_title":["Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-Associated Protein 9 Mediated Knockout Reveals Functions of the <i>yellow-y</i> Gene in <i>Spodoptera litura</i>."],"pmcid":["PMC7839173"],"pubmed_authors":["Liu XL","Ze LJ","Yan Q","Peng YC","Zhang J","Han WK","Dong SL","Yang YL"],"additional_accession":[]},"is_claimable":false,"name":"Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-Associated Protein 9 Mediated Knockout Reveals Functions of the <i>yellow-y</i> Gene in <i>Spodoptera litura</i>.","description":"<i>Yellow</i> genes are thought to be involved in the melanin biosynthetic pathway and play a crucial role in pigmentation reactions in insects. However, little research has been done on <i>yellow</i> genes in lepidopteran pests. To clarify the function of one of the <i>yellow</i> genes (<i>yellow-y</i>) in <i>Spodoptera litura</i>, we cloned the full-length of <i>yellow-y</i>, and investigated its spatial and temporal expression profiles by quantitative real-time PCR (qPCR). It revealed that <i>yellow-y</i> was highly expressed in larva of fourth, fifth, and sixth instars, as well as in epidermis (Ep), fat bodies (FB), Malpighian tubes (MT), and midguts (MG) of the larvae; whereas it was expressed in very low levels in different tissues of adults, and was almost undetected in pupa. This e","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2025-04-19T05:46:28.725Z","creation":"2021-02-21T05:14:15Z"},"accession":"S-EPMC7839173","cross_references":{"pubmed":["33519520"],"doi":["10.3389/fphys.2020.615391"]}}