{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rossi I"],"funding":["NIDDK NIH HHS","National Institutes of Health"],"pagination":["539-542"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7870514"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["169(3)"],"pubmed_abstract":["<h4>Background</h4>Obesity and type 2 diabetes mellitus are associated with elevated levels of inflammatory markers. This chronic inflammation is known to contribute to increased risk of cardiovascular disease in these populations. Laparoscopic Roux-en-Y gastric bypass is associated with a high rate of diabetes remission. We hypothesize that laparoscopic Roux-en-Y gastric bypass decreases systemic inflammatory markers and cardiovascular disease risk factors in obese diabetics.<h4>Methods</h4>This was a single-institution prospective cohort study of 61 obese patients with type 2 diabetes mellitus. A total of 30 patients underwent laparoscopic Roux-en-Y gastric bypass surgery, and 31 patients underwent standard medical therapy with diabetes support and education. Collected data included preo"],"journal":["Surgery"],"pubmed_title":["Roux-en-Y gastric bypass decreases serum inflammatory markers and cardiovascular risk factors in obese diabetics."],"pmcid":["PMC7870514"],"funding_grant_id":["K23 DK075907"],"pubmed_authors":["Torquati A","Rossi I","Spagnoli A","Poirier J","Omotosho P"],"additional_accession":[]},"is_claimable":false,"name":"Roux-en-Y gastric bypass decreases serum inflammatory markers and cardiovascular risk factors in obese diabetics.","description":"<h4>Background</h4>Obesity and type 2 diabetes mellitus are associated with elevated levels of inflammatory markers. This chronic inflammation is known to contribute to increased risk of cardiovascular disease in these populations. Laparoscopic Roux-en-Y gastric bypass is associated with a high rate of diabetes remission. We hypothesize that laparoscopic Roux-en-Y gastric bypass decreases systemic inflammatory markers and cardiovascular disease risk factors in obese diabetics.<h4>Methods</h4>This was a single-institution prospective cohort study of 61 obese patients with type 2 diabetes mellitus. A total of 30 patients underwent laparoscopic Roux-en-Y gastric bypass surgery, and 31 patients underwent standard medical therapy with diabetes support and education. Collected data included preo","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Mar","modification":"2025-04-18T12:11:44.078Z","creation":"2025-04-06T21:48:22.072Z"},"accession":"S-EPMC7870514","cross_references":{"pubmed":["33168209"],"doi":["10.1016/j.surg.2020.09.039"]}}