biostudies-literatureUnknown11(1)Bay P<h4>Background</h4>Systemic rheumatic diseases (SRDs) are a group of inflammatory disorders that can require intensive care unit (ICU) admission because of multiorgan involvement with end-organ failure(s). Critically ill SRD patients requiring extracorporeal membrane oxygenation (ECMO) were studied to gain insight into their characteristics and outcomes.<h4>Methods</h4>This French monocenter, retrospective study included all SRD patients requiring venovenous (VV)- or venoarterial (VA)-ECMO admitted to a 26-bed ECMO-dedicated ICU from January 2006 to February 2020. The primary endpoint was in-hospital mortality.<h4>Results</h4>Ninety patients (male/female ratio: 0.5; mean age at admission: 41.6 ± 15.2 years) admitted to the ICU received VA/VV-ECMO, respectively, for an SRD-related flare (n Annals of intensive care29https://www.ebi.ac.uk/biostudies/studies/S-EPMC7871308biostudies-literatureOutcomes of severe systemic rheumatic disease patients requiring extracorporeal membrane oxygenation.PMC7871308Luyt CEHekimian GBay PDesnos CCohen-Aubart FCombes AMathian ALebreton GNieszkowska ABrechot NSchmidt MLeprince PDemondion PPineton de Chambrun MAmoura ZChommeloux JfalseOutcomes of severe systemic rheumatic disease patients requiring extracorporeal membrane oxygenation.<h4>Background</h4>Systemic rheumatic diseases (SRDs) are a group of inflammatory disorders that can require intensive care unit (ICU) admission because of multiorgan involvement with end-organ failure(s). Critically ill SRD patients requiring extracorporeal membrane oxygenation (ECMO) were studied to gain insight into their characteristics and outcomes.<h4>Methods</h4>This French monocenter, retrospective study included all SRD patients requiring venovenous (VV)- or venoarterial (VA)-ECMO admitted to a 26-bed ECMO-dedicated ICU from January 2006 to February 2020. The primary endpoint was in-hospital mortality.<h4>Results</h4>Ninety patients (male/female ratio: 0.5; mean age at admission: 41.6 ± 15.2 years) admitted to the ICU received VA/VV-ECMO, respectively, for an SRD-related flare (n 2021-01-01T00:00:00Z2021 Feb2026-07-14T14:39:13.035Z2025-02-19T04:32:12.062ZS-EPMC78713083355976310.1186/s13613-021-00819-3