{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lala A"],"funding":["National Institute of Neurological Disorders and Stroke","U.S. Department of Health and Human Services","NHLBI NIH HHS","National Heart, Lung, and Blood Institute","National Institutes of Health","Canadian Institutes of Health Research"],"pagination":["1769-1778.e7"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7874266"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["162(6)"],"pubmed_abstract":["<h4>Objectives</h4>To determine the frequency and risk factors for non-home discharge (NHD) and its association with clinical outcomes and quality of life (QOL) at 1 year following cardiac surgery in patients with ischemic mitral regurgitation (IMR).<h4>Methods</h4>Discharge disposition was evaluated in 552 patients enrolled in trials of severe or moderate IMR. Patient and in-hospital factors associated with NHD were identified using logistic regression. Subsequently, association of NHD with 1-year mortality, serious adverse events (SAEs), and QOL was assessed.<h4>Results</h4>NHD was observed in 30% (154/522) with 25% (n = 71/289) in moderate and 36% (n = 83/233) in patients with severe IMR (unadjusted P = .006), a difference not significant after including age (5-year change: adjusted odd"],"journal":["The Journal of thoracic and cardiovascular surgery"],"pubmed_title":["Risk for non-home discharge following surgery for ischemic mitral valve disease."],"pmcid":["PMC7874266"],"funding_grant_id":["UM1 HL117924","U01 HL088942","UM1 HL088955"],"pubmed_authors":["Williams M","Smith CR","Dobrev E","Williams D","Miller MA","Kilcullen N","Puskas JD","Cardiothoracic Surgical Trials Network (CTSN) Working Group","Keteyian SJ","Taddei-Peters WC","Settele N","Dent JM","O'Gara PT","Kern J","Richenbacher W","Headlee M","Moskowitz AJ","Magee P","Woo A","Michler RE","Zeng X","Furie KL","Argenziano M","Jakobleff W","Pellerin M","Sellke F","Mociornita A","Nohria A","D'Alessandro DA","Yancy CW","Williams P","Corcoran PC","Hasan A","Carrier M","Trichon BH","Shavalle D","Van Patten D","Santos M","Ye X","Miller R","Neill AA","Baer J","Dang M","Malgaard H","Lala A","Yau T","Basile F","Ikonomidis JS","Walsh MN","Christakis G","Miller F","Karkhanis R","Smith RL","Kypson AP","Sai-Sudhakar C","DeRose JJ","Mullen JC","Joyner C","Voisine P","Moussa F","Byington R","Prieto I","Williams JB","Cohen G","Doud K","Sookraj N","Clarke PA","O'Connor K","Young CA","Wechsler AS","Rao V","Perrault LP","Dixon DO","Charles EJ","Dionne J","Goldfarb S","Stevens LM","Smith PK","Hampton LC","Meyer S","Acker MA","Baio K","Ballivian T","Greenberg A","Chen Y","Gupta L","Romar L","Yerokun BA","Cohn L","Bowdish M","Weglinski M","Garrard L","Mack M","Garcia M","El-Hamamsy I","Atluri P","Palumbo R","Berroteran L","Spertus J","Ailawadi G","Naka Y","Browndyke J","Fleming S","Dickert N","O'Sullivan K","Basmadjian AJ","Aldred H","Holubkov R","Ryan W","Liu X","Moquete E","Murphy M","Kuurstra E","David T","Bonneau D","Verma S","Harris M","Burgess A","Cartier R","Bell D","Dolney D","Errett L","Berry MF","Speir AM","Giannetti N","Lackner P","Nanney T","Ralph J","Chang HL","Fecteau J","Sreekanth S","McDavid A","Mangusan R","Horvath KA","Caulder R","Gelijns AC","Burks S","Levitan R","Bello R","Jonathan Lacharite SR","Javadifar S","Denault A","Brawner CA","Bowdish ME","Alexander JH","Page P","Overbey J","Stewart A","Pattakos G","Moody H","Bagiella E","Harrison JK","Matthews R","Williams DO","Cusimano RJ","Murkin JM","Feder-Elituv R","Sweeney DK","Akers B","Mathew JP","Johnston K","Keilani S","Aranki S","Swayze R","Weisel RD","Jacobs A","Welsh S","Wiggers H","Parsa CJ","Shepard SA","Gardner TJ","Chase M","Chen FY","Siegenthaler MP","Sankovic K","Rose EA","Mack MJ","Gombos IK","Lee A","Milano CA","Senechal M","Bouchard D","Chang H","Foo J","Grayburn P","Gillinov AM","Roberts WC","Fredericks S","Farkouh M","Slaughter M","Fremes SE","Jeffries NO","Goldsmith L","Adams J","Thourani VH","Dussault G","Keim J","Wood C","Latter D","Spevak D","Tong BC","Starnes VA","Wang A","Shekar P","Iraola M","Parides MK","Peterson MD","Keyte S","Shell LE","Kinn B","Kron IL","Taub C","Beach D","Woo YJ","Blackstone EH","Ad N","Villanueva R","Bull DA","Fang JC","Nielsen SL","Haigney M","Gammie JS","Stevenson LW","Davidson M","Groh MA","Pinney S","Demers P","Sirois C","Ferguson TB","Guyton R","Rodriguez E","Tanguay JF","Feindel C","Hung D","Goldstein DJ","Buxton D","Bolman RM","Gahring K","Hung J","Geller NL","Choy J","Solankhi N","Conboy D","Schwartz A","Noiseux N","Dagenais F","Glower DD","Leong-Poi H","Adame T","Whitman C","Lawrence R","Geither C","Kirkwood K","Couper G","Birks E","Gordon D","Mayer ML","Toulgoat-Dubois Y","Ascheim DD","O'Neal A"],"additional_accession":[]},"is_claimable":false,"name":"Risk for non-home discharge following surgery for ischemic mitral valve disease.","description":"<h4>Objectives</h4>To determine the frequency and risk factors for non-home discharge (NHD) and its association with clinical outcomes and quality of life (QOL) at 1 year following cardiac surgery in patients with ischemic mitral regurgitation (IMR).<h4>Methods</h4>Discharge disposition was evaluated in 552 patients enrolled in trials of severe or moderate IMR. Patient and in-hospital factors associated with NHD were identified using logistic regression. Subsequently, association of NHD with 1-year mortality, serious adverse events (SAEs), and QOL was assessed.<h4>Results</h4>NHD was observed in 30% (154/522) with 25% (n = 71/289) in moderate and 36% (n = 83/233) in patients with severe IMR (unadjusted P = .006), a difference not significant after including age (5-year change: adjusted odd","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2026-05-01T11:39:19.964Z","creation":"2022-02-09T08:02:35.355Z"},"accession":"S-EPMC7874266","cross_references":{"pubmed":["32307181"],"doi":["10.1016/j.jtcvs.2020.02.084"]}}