biostudies-literatureLala ANational Institute of Neurological Disorders and StrokeU.S. Department of Health and Human ServicesNHLBI NIH HHSNational Heart, Lung, and Blood InstituteNational Institutes of HealthCanadian Institutes of Health Research1769-1778.e7https://www.ebi.ac.uk/biostudies/studies/S-EPMC7874266biostudies-literatureUnknown162(6)<h4>Objectives</h4>To determine the frequency and risk factors for non-home discharge (NHD) and its association with clinical outcomes and quality of life (QOL) at 1 year following cardiac surgery in patients with ischemic mitral regurgitation (IMR).<h4>Methods</h4>Discharge disposition was evaluated in 552 patients enrolled in trials of severe or moderate IMR. Patient and in-hospital factors associated with NHD were identified using logistic regression. Subsequently, association of NHD with 1-year mortality, serious adverse events (SAEs), and QOL was assessed.<h4>Results</h4>NHD was observed in 30% (154/522) with 25% (n = 71/289) in moderate and 36% (n = 83/233) in patients with severe IMR (unadjusted P = .006), a difference not significant after including age (5-year change: adjusted oddThe Journal of thoracic and cardiovascular surgeryRisk for non-home discharge following surgery for ischemic mitral valve disease.PMC7874266UM1 HL117924U01 HL088942UM1 HL088955Williams MSmith CRDobrev EWilliams DMiller MAKilcullen NPuskas JDCardiothoracic Surgical Trials Network (CTSN) Working GroupKeteyian SJTaddei-Peters WCSettele NDent JMO'Gara PTKern JRichenbacher WHeadlee MMoskowitz AJMagee PWoo AMichler REZeng XFurie KLArgenziano MJakobleff WPellerin MSellke FMociornita ANohria AD'Alessandro DAYancy CWWilliams PCorcoran PCHasan ACarrier MTrichon BHShavalle DVan Patten DSantos MYe XMiller RNeill AABaer JDang MMalgaard HLala AYau TBasile FIkonomidis JSWalsh MNChristakis GMiller FKarkhanis RSmith RLKypson APSai-Sudhakar CDeRose JJMullen JCJoyner CVoisine PMoussa FByington RPrieto IWilliams JBCohen GDoud KSookraj NClarke PAO'Connor KYoung CAWechsler ASRao VPerrault LPDixon DOCharles EJDionne JGoldfarb SStevens LMSmith PKHampton LCMeyer SAcker MABaio KBallivian TGreenberg AChen YGupta LRomar LYerokun BACohn LBowdish MWeglinski MGarrard LMack MGarcia MEl-Hamamsy IAtluri PPalumbo RBerroteran LSpertus JAilawadi GNaka YBrowndyke JFleming SDickert NO'Sullivan KBasmadjian AJAldred HHolubkov RRyan WLiu XMoquete EMurphy MKuurstra EDavid TBonneau DVerma SHarris MBurgess ACartier RBell DDolney DErrett LBerry MFSpeir AMGiannetti NLackner PNanney TRalph JChang HLFecteau JSreekanth SMcDavid AMangusan RHorvath KACaulder RGelijns ACBurks SLevitan RBello RJonathan Lacharite SRJavadifar SDenault ABrawner CABowdish MEAlexander JHPage POverbey JStewart APattakos GMoody HBagiella EHarrison JKMatthews RWilliams DOCusimano RJMurkin JMFeder-Elituv RSweeney DKAkers BMathew JPJohnston KKeilani SAranki SSwayze RWeisel RDJacobs AWelsh SWiggers HParsa CJShepard SAGardner TJChase MChen FYSiegenthaler MPSankovic KRose EAMack MJGombos IKLee AMilano CASenechal MBouchard DChang HFoo JGrayburn PGillinov AMRoberts WCFredericks SFarkouh MSlaughter MFremes SEJeffries NOGoldsmith LAdams JThourani VHDussault GKeim JWood CLatter DSpevak DTong BCStarnes VAWang AShekar PIraola MParides MKPeterson MDKeyte SShell LEKinn BKron ILTaub CBeach DWoo YJBlackstone EHAd NVillanueva RBull DAFang JCNielsen SLHaigney MGammie JSStevenson LWDavidson MGroh MAPinney SDemers PSirois CFerguson TBGuyton RRodriguez ETanguay JFFeindel CHung DGoldstein DJBuxton DBolman RMGahring KHung JGeller NLChoy JSolankhi NConboy DSchwartz ANoiseux NDagenais FGlower DDLeong-Poi HAdame TWhitman CLawrence RGeither CKirkwood KCouper GBirks EGordon DMayer MLToulgoat-Dubois YAscheim DDO'Neal AfalseRisk for non-home discharge following surgery for ischemic mitral valve disease.<h4>Objectives</h4>To determine the frequency and risk factors for non-home discharge (NHD) and its association with clinical outcomes and quality of life (QOL) at 1 year following cardiac surgery in patients with ischemic mitral regurgitation (IMR).<h4>Methods</h4>Discharge disposition was evaluated in 552 patients enrolled in trials of severe or moderate IMR. Patient and in-hospital factors associated with NHD were identified using logistic regression. Subsequently, association of NHD with 1-year mortality, serious adverse events (SAEs), and QOL was assessed.<h4>Results</h4>NHD was observed in 30% (154/522) with 25% (n = 71/289) in moderate and 36% (n = 83/233) in patients with severe IMR (unadjusted P = .006), a difference not significant after including age (5-year change: adjusted odd2021-01-01T00:00:00Z2021 Dec2026-05-01T11:39:19.964Z2022-02-09T08:02:35.355ZS-EPMC78742663230718110.1016/j.jtcvs.2020.02.084