{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lei L"],"funding":["Medical Research Council","National Natural Science Foundation of China","UK MRC DETER-XDR-China-HUB","Biotechnology and Biological Sciences Research Council"],"pagination":["242-251"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7889244"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(1)"],"pubmed_abstract":["Mobile colistin resistance gene <i>mcr-1</i> and extended-spectrum <i>β</i>-lactamase gene <i>bla</i> <sub>CTX-M</sub> are highly prevalent in human - and pet-derived bacteria. Isolation of identical strains of <i>mcr-1</i>-positive <i>Escherichia coli</i> (MCRPEC) or <i>bla</i> <sub>CTX-M</sub>-positive <i>E. coli</i> (CTX-MPEC) from pets and humans highlighted the potential for co-colonization of antibiotic-resistant bacteria which can be a risk for dissemination of resistance genes. In this study, the prevalence of <i>mcr-1</i> and <i>bla</i> <sub>CTX-M</sub> carriage from rectal swabs in 299 families (dogs and their owners) were 2.7 and 5.3%, respectively. We identified a significant association of <i>mcr-1</i> carriage between dogs and their owners. Whilst antibiotic use in the previo"],"journal":["Emerging microbes & infections"],"pubmed_title":["Prevalence and risk analysis of mobile colistin resistance and extended-spectrum &lt;i&gt;β&lt;/i&gt;-lactamase genes carriage in pet dogs and their owners: a population based cross-sectional study."],"pmcid":["PMC7889244"],"funding_grant_id":["81861138051","BB/R012776/1","MR/S013768/2","81991535","MR/S013768/1"],"pubmed_authors":["Lei L","Zou Z","Shi L","Cai C","Shen J","He J","Walsh TR","Liu Q","Zhong Y","Wang Y","Yang D","Jia J"],"additional_accession":[]},"is_claimable":false,"name":"Prevalence and risk analysis of mobile colistin resistance and extended-spectrum &lt;i&gt;β&lt;/i&gt;-lactamase genes carriage in pet dogs and their owners: a population based cross-sectional study.","description":"Mobile colistin resistance gene <i>mcr-1</i> and extended-spectrum <i>β</i>-lactamase gene <i>bla</i> <sub>CTX-M</sub> are highly prevalent in human - and pet-derived bacteria. Isolation of identical strains of <i>mcr-1</i>-positive <i>Escherichia coli</i> (MCRPEC) or <i>bla</i> <sub>CTX-M</sub>-positive <i>E. coli</i> (CTX-MPEC) from pets and humans highlighted the potential for co-colonization of antibiotic-resistant bacteria which can be a risk for dissemination of resistance genes. In this study, the prevalence of <i>mcr-1</i> and <i>bla</i> <sub>CTX-M</sub> carriage from rectal swabs in 299 families (dogs and their owners) were 2.7 and 5.3%, respectively. We identified a significant association of <i>mcr-1</i> carriage between dogs and their owners. Whilst antibiotic use in the previo","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2026-04-18T01:18:38.721Z","creation":"2021-02-26T08:12:57Z"},"accession":"S-EPMC7889244","cross_references":{"pubmed":["33502946"],"doi":["10.1080/22221751.2021.1882884"]}}