biostudies-literatureUnknown67(3)Del Ser T<h4>Background</h4>The older population has been especially affected by the severe acute respiratory syndrome coronavirus 2 pandemic (COVID-19).<h4>Objective</h4>The aim of the study was to explore the incidence, severity, mortality rate, clinical features, and risk factors of symptoms of COVID-19 in home-dwelling older people, and its association with type of residence, cognitive deterioration, and neurodegenerative diseases.<h4>Methods</h4>Data about symptoms of COVID-19 were collected through a telephone survey in the cohort of 913 older volunteers of the Vallecas Project, aged 75-90 years, most of them (902) home-dwelling, in Madrid, Spain. The association of demographic and anthropometric measures, genetic polymorphisms, comorbidities, life habits, type of residence, and frailty surroGerontology281-289https://www.ebi.ac.uk/biostudies/studies/S-EPMC7900450biostudies-literatureResidence, Clinical Features, and Genetic Risk Factors Associated with Symptoms of COVID-19 in a Cohort of Older People in Madrid.PMC7900450Zea-Sevilla MAFrades BSaiz LValenti MRabano AMedina MAlfayate EGarcia-Lopez FJFernandez-Blazquez MACalero OCalero MDel Ser TfalseResidence, Clinical Features, and Genetic Risk Factors Associated with Symptoms of COVID-19 in a Cohort of Older People in Madrid.<h4>Background</h4>The older population has been especially affected by the severe acute respiratory syndrome coronavirus 2 pandemic (COVID-19).<h4>Objective</h4>The aim of the study was to explore the incidence, severity, mortality rate, clinical features, and risk factors of symptoms of COVID-19 in home-dwelling older people, and its association with type of residence, cognitive deterioration, and neurodegenerative diseases.<h4>Methods</h4>Data about symptoms of COVID-19 were collected through a telephone survey in the cohort of 913 older volunteers of the Vallecas Project, aged 75-90 years, most of them (902) home-dwelling, in Madrid, Spain. The association of demographic and anthropometric measures, genetic polymorphisms, comorbidities, life habits, type of residence, and frailty surro2021-01-01T00:00:00Z20212025-06-01T01:56:39.697Z2025-06-01T01:56:39.697ZS-EPMC79004503342939410.1159/000513182