{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Subhedar NV"],"funding":["Medical Research Council","National Institute for Health Research (NIHR)"],"pagination":["e000897"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7903123"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["5(1)"],"pubmed_abstract":["<h4>Objective</h4>To describe temporal changes in inhaled nitric oxide (iNO) use in English neonatal units between 2010 and 2015.<h4>Design</h4>Retrospective analysis using data extracted from the National Neonatal Research Database.<h4>Setting</h4>All National Health Service neonatal units in England.<h4>Patients</h4>Infants of all gestational ages born 2010-2015 admitted to a neonatal unit and received intensive care.<h4>Main outcome measures</h4>Proportion of infants who received iNO; age at initiation and duration of iNO use.<h4>Results</h4>4.9% (6346/129 883) of infants received iNO; 31% (1959/6346) were born <29 weeks, 18% (1152/6346) 29-33 weeks and 51% (3235/6346)>34 weeks of gestation. Between epoch 1 (2010-2011) and epoch 3 (2014-2015), there was (1) an increase in the proportion"],"journal":["BMJ paediatrics open"],"pubmed_title":["Increase in the use of inhaled nitric oxide in neonatal intensive care units in England: a retrospective population study."],"pmcid":["PMC7903123"],"funding_grant_id":["NIHR300617","MR/N008405/1"],"pubmed_authors":["Seagrave C","Sandhu S","Zengeya S","Obi O","Oliver C","Balal S","Ben Obi PA","Shephard R","Wickham T","Halpert P","James M","Banjoko O","Brooke N","Maddock N","Cusack J","Bontea A","Baird J","Martin P","Dixon H","Emery F","Kapur J","Murthy V","Garbash M","Sanghavi R","Jain N","Nicholl R","Kendall G","Jain M","Babirecki M","Leith W","Abu-Harb M","Vasu V","Nash M","Gibson D","Theron M","Pai V","Rewitzky G","Whincup G","Birch J","Rekha S","Foo A","Adiotomre P","Aucharaz K","Lee G","Vamvakiti K","Seal S","Rhodes S","Nath P","Fedee J","Ogundiya A","Salgia S","Jawad S","Schwarz K","Chang J","Zipitis C","McIntyre J","Sivashankar S","Holman J","Aung YM","Gupta R","Webb D","Khashu M","Munyard P","Mittal A","Gupta S","Gupta V","Bate T","Adams E","Mannan K","Harry L","Olabi A","Brearey S","Mattara S","Knight C","Deketelaere A","Halpern L","Negrine R","Settle P","Paul N","Aung Y","Paul S","Bhat R","Cairns P","Gupta A","Groves C","Amess P","Gupta C","Battersby C","Hassan A","Surana P","Krishnamurthy GR","Winder L","Abdul Khader K","Athiraman N","Kefas J","Selter M","Brennan N","Reddy C","Miall L","Winckworth L","Evans I","Mack K","Eaton M","Allwood A","Reddy A","Oughham K","Chuang SL","Sullivan C","Tyszcuzk L","Heal C","Wong LM","D'Amore A","Hasib A","Lal M","Misra I","Deshpande ES","Jones S","Abdul-Malik B","Johnson M","Bird","Thiagarajan P","Dewhurst C","Hartung R","Gaili H","Rawlingson C","Bastani P","Aladangady N","Huddy C","Dyke M","Garr R","Hulse E","Kamalanathan A","Ali I","Whitehead G","Dale A","Narayanan S","Muogbo D","Gale C","Pandey P","Grosdenier M","Kamath P","Anderson J","Kisat H","Kumar H","Kairamkonda V","Wardle S","Ambadkar","Subhedar NV","McDevitt K","Edi-Osagie N","UK Neonatal Collaborative"],"additional_accession":[]},"is_claimable":false,"name":"Increase in the use of inhaled nitric oxide in neonatal intensive care units in England: a retrospective population study.","description":"<h4>Objective</h4>To describe temporal changes in inhaled nitric oxide (iNO) use in English neonatal units between 2010 and 2015.<h4>Design</h4>Retrospective analysis using data extracted from the National Neonatal Research Database.<h4>Setting</h4>All National Health Service neonatal units in England.<h4>Patients</h4>Infants of all gestational ages born 2010-2015 admitted to a neonatal unit and received intensive care.<h4>Main outcome measures</h4>Proportion of infants who received iNO; age at initiation and duration of iNO use.<h4>Results</h4>4.9% (6346/129 883) of infants received iNO; 31% (1959/6346) were born <29 weeks, 18% (1152/6346) 29-33 weeks and 51% (3235/6346)>34 weeks of gestation. Between epoch 1 (2010-2011) and epoch 3 (2014-2015), there was (1) an increase in the proportion","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2025-04-22T08:16:10.272Z","creation":"2021-03-12T08:18:37Z"},"accession":"S-EPMC7903123","cross_references":{"pubmed":["33705500"],"doi":["10.1136/bmjpo-2020-000897"]}}