biostudies-literatureBian YNEI NIH HHSS92-S97https://www.ebi.ac.uk/biostudies/studies/S-EPMC7904972biostudies-literatureUnknown37(3S)<h4>Purpose</h4>To describe a reversible syndrome of epiphora, functional punctal stenosis, and chronic pretarsal conjunctivitis associated with corticosteroid or corticosteroid-antibiotic eyedrop use.<h4>Methods</h4>This is an Institutional Review Board-approved retrospective review of patients diagnosed with epiphora, punctal stenosis, and chronic conjunctivitis by a single surgeon (B.J.W.). These patients were subsequently invited to participate in a prospective study involving allergy skin patch testing for ophthalmic drops, common excipients, and active ingredients.<h4>Results</h4>Thirteen patients received a diagnosis of punctal congestion syndrome. The average age was 63 years (range, 41-93) and 69.2% were female. Findings were bilateral in 61.5%. All had used preserved drops in theOphthalmic plastic and reconstructive surgeryPunctal Congestion Syndrome: A Reversible, Functional Punctal Stenosis Causing Epiphora in the Setting of Chronic Pretarsal Conjunctivitis.PMC7904972P30 EY002162Zemsky CBelsito DVScofield-Kaplan SMGhadiali LBian YDagi Glass LRCampagnoli TSallee BWinn BJfalsePunctal Congestion Syndrome: A Reversible, Functional Punctal Stenosis Causing Epiphora in the Setting of Chronic Pretarsal Conjunctivitis.<h4>Purpose</h4>To describe a reversible syndrome of epiphora, functional punctal stenosis, and chronic pretarsal conjunctivitis associated with corticosteroid or corticosteroid-antibiotic eyedrop use.<h4>Methods</h4>This is an Institutional Review Board-approved retrospective review of patients diagnosed with epiphora, punctal stenosis, and chronic conjunctivitis by a single surgeon (B.J.W.). These patients were subsequently invited to participate in a prospective study involving allergy skin patch testing for ophthalmic drops, common excipients, and active ingredients.<h4>Results</h4>Thirteen patients received a diagnosis of punctal congestion syndrome. The average age was 63 years (range, 41-93) and 69.2% were female. Findings were bilateral in 61.5%. All had used preserved drops in the2021-01-01T00:00:00Z2021 May-Jun 012025-04-03T22:46:27.821Z2022-02-11T13:37:40.331ZS-EPMC79049723289012010.1097/iop.000000000000184010.1097/IOP.0000000000001840