biostudies-literaturede Pinieux GLigue Contre le CancerFondation ARC pour la Recherche sur le CancerAgence Nationale de la RechercheInstitut National Du CancerEUROPEAN COMMISSION (EU) EURACANe0246958https://www.ebi.ac.uk/biostudies/studies/S-EPMC7906477biostudies-literatureUnknown16(2)<h4>Background</h4>Since 2010, nationwide networks of reference centers for sarcomas (RREPS/NETSARC/RESOS) collected and prospectively reviewed all cases of sarcomas and connective tumors of intermediate malignancy (TIM) in France.<h4>Methods</h4>The nationwide incidence of sarcoma or TIM (2013-2016) was measured using the 2013 WHO classification and confirmed by a second independent review by expert pathologists. Simple clinical characteristics, yearly variations and correlation of incidence with published clinical trials are presented and analyzed.<h4>Results</h4>Over 150 different histological subtypes are reported from the 25172 patients with sarcomas (n = 18712, 74,3%) or TIM (n = 6460, 25.7%), with n = 5838, n = 6153, n = 6654, and n = 6527 yearly cases from 2013 to 2016. Over these PloS oneNationwide incidence of sarcomas and connective tissue tumors of intermediate malignancy over four years using an expert pathology review network.PMC7906477RESOSInstitut Convergence PLASCAN (17-CONV-0002)RREPSUnicancerLabEx DEvweCAN (ANR-10-LABX-0061),EC 739521NETSARCINTERSARCCanopeeNETSARC+Mesli NPenel NMescam LAngot ENeuville ALeroux AMacagno NCharon-Barra Cde Pinieux GMoreau AJean-Denis MCoindre JMToulmonde MGouin FRanchere DKaranian MChateau MCCollin FChemin-Airiau CRochaix PCourreges JBLe Guellec SDemuret ABouvier CBlay JYBazille CLae MCroce SRobin YMTerrier PStock NEmile JFMishellany FLe Cesne AChabaud SBirtwisle-Peyrottes IWeinbreck NBrouchet ADucimetiere FLe Loarer FNetSarc/RePPS/ResSos and French Sarcoma Group- Groupe d’Etude des Tumeurs Osseuses (GSF-GETO) networksBerchoud JGhnassia JPLarousserie FAubert SChetaille BItaliano AQuintin-Rouet IDelfour CFayet YPommepuy IOrtonne NDoucet LBatistella MValo IfalseNationwide incidence of sarcomas and connective tissue tumors of intermediate malignancy over four years using an expert pathology review network.<h4>Background</h4>Since 2010, nationwide networks of reference centers for sarcomas (RREPS/NETSARC/RESOS) collected and prospectively reviewed all cases of sarcomas and connective tumors of intermediate malignancy (TIM) in France.<h4>Methods</h4>The nationwide incidence of sarcoma or TIM (2013-2016) was measured using the 2013 WHO classification and confirmed by a second independent review by expert pathologists. Simple clinical characteristics, yearly variations and correlation of incidence with published clinical trials are presented and analyzed.<h4>Results</h4>Over 150 different histological subtypes are reported from the 25172 patients with sarcomas (n = 18712, 74,3%) or TIM (n = 6460, 25.7%), with n = 5838, n = 6153, n = 6654, and n = 6527 yearly cases from 2013 to 2016. Over these 2021-01-01T00:00:00Z20212026-05-09T08:54:26.726Z2021-03-06T08:16:38ZS-EPMC79064773363091810.1371/journal.pone.0246958