{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gong T"],"funding":["Science and Technology Program of Guizhou Province","National Natural Science Foundation of China","Scientific Research Cooperation Project with America and Oceania Region, Ministry of Education"],"pagination":["437"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7916009"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(2)"],"pubmed_abstract":["Testicular expression of taste receptor type 1 subunit 3 (T1R3), a sweet/umami taste receptor, has been implicated in spermatogenesis and steroidogenesis in mice. We explored the role of testicular T1R3 in porcine postnatal development using the Congjiang Xiang pig, a rare Chinese miniature pig breed. Based on testicular weights, morphology, and testosterone levels, four key developmental stages were identified in the pig at postnatal days 15-180 (prepuberty: 30 day; early puberty: 60 day; late puberty: 90 day; sexual maturity: 120 day). During development, testicular T1R3 exhibited stage-dependent and cell-specific expression patterns. In particular, T1R3 levels increased significantly from prepuberty to puberty (<i>p</i> < 0.05), and expression remained high until sexual maturity (<i>p</"],"journal":["Animals : an open access journal from MDPI"],"pubmed_title":["Longitudinal Expression of Testicular <i>TAS1R3</i> from Prepuberty to Sexual Maturity in Congjiang Xiang Pigs."],"pmcid":["PMC7916009"],"funding_grant_id":["JWSM[2016]2191","QKHPTRC[2018]5436, QKHJC[2020]1Y135 and QKHJC[2020]1Z028","31702117"],"pubmed_authors":["Wan S","Gong T","Yang Y","Li Z","Wang W","Meng L","Chen X","Xu H","Mu Q","Xu Y"],"additional_accession":[]},"is_claimable":false,"name":"Longitudinal Expression of Testicular <i>TAS1R3</i> from Prepuberty to Sexual Maturity in Congjiang Xiang Pigs.","description":"Testicular expression of taste receptor type 1 subunit 3 (T1R3), a sweet/umami taste receptor, has been implicated in spermatogenesis and steroidogenesis in mice. We explored the role of testicular T1R3 in porcine postnatal development using the Congjiang Xiang pig, a rare Chinese miniature pig breed. Based on testicular weights, morphology, and testosterone levels, four key developmental stages were identified in the pig at postnatal days 15-180 (prepuberty: 30 day; early puberty: 60 day; late puberty: 90 day; sexual maturity: 120 day). During development, testicular T1R3 exhibited stage-dependent and cell-specific expression patterns. In particular, T1R3 levels increased significantly from prepuberty to puberty (<i>p</i> < 0.05), and expression remained high until sexual maturity (<i>p</","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Feb","modification":"2026-04-18T01:20:22.99Z","creation":"2021-03-03T08:08:17Z"},"accession":"S-EPMC7916009","cross_references":{"pubmed":["33567555"],"doi":["10.3390/ani11020437"]}}