{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rojas SA"],"funding":["California Department of Public Health","Centers for Disease Control and Prevention","NCHHSTP CDC HHS","Health Resources and Services Administration","Gilead Sciences"],"pagination":["412-423"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7917265"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["5(3)"],"pubmed_abstract":["Hepatitis C virus (HCV) is a major cause of cirrhosis, liver cancer, and mortality in the United States. We assessed the effectiveness of decentralized HCV treatment delivered by nurse practitioners (NPs), primary care physicians (PMDs), or an infectious disease physician (ID MD) using direct-acting antivirals in a Federally Qualified Health Center (FQHC) in urban San Diego, CA. We conducted a cross-sectional analysis of 1,261 patients who received treatment from six NPs, 10 PMDs, and one ID MD practicing in 10 clinics between January 2014 and January 2020. Care was delivered based on the Extension for Community Healthcare Outcomes (Project ECHO) model with one hub and nine spokes. HCV was deemed cured if a patient had a sustained virologic response (SVR) after 12 weeks of treatment (SVR12"],"journal":["Hepatology communications"],"pubmed_title":["Effectiveness of a Decentralized Hub and Spoke Model for the Treatment of Hepatitis C Virus in a Federally Qualified Health Center."],"pmcid":["PMC7917265"],"funding_grant_id":["U51 PS003924","HIV Workforce Development Grant / #0677‐019‐101","FOA FS12‐1209FFHP12 / U51PS003924‐01","HCV Training Grant / Award #15‐10749","FOCUS PROGRAM"],"pubmed_authors":["Northrup A","Godino JG","Khasira M","Tam A","Asmus L","Frenette C","Rojas SA","Ramers CB"],"additional_accession":[]},"is_claimable":false,"name":"Effectiveness of a Decentralized Hub and Spoke Model for the Treatment of Hepatitis C Virus in a Federally Qualified Health Center.","description":"Hepatitis C virus (HCV) is a major cause of cirrhosis, liver cancer, and mortality in the United States. We assessed the effectiveness of decentralized HCV treatment delivered by nurse practitioners (NPs), primary care physicians (PMDs), or an infectious disease physician (ID MD) using direct-acting antivirals in a Federally Qualified Health Center (FQHC) in urban San Diego, CA. We conducted a cross-sectional analysis of 1,261 patients who received treatment from six NPs, 10 PMDs, and one ID MD practicing in 10 clinics between January 2014 and January 2020. Care was delivered based on the Extension for Community Healthcare Outcomes (Project ECHO) model with one hub and nine spokes. HCV was deemed cured if a patient had a sustained virologic response (SVR) after 12 weeks of treatment (SVR12","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Mar","modification":"2026-06-02T12:45:13.632Z","creation":"2026-04-19T03:09:29.973Z"},"accession":"S-EPMC7917265","cross_references":{"pubmed":["33681676"],"doi":["10.1002/hep4.1617"]}}