{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["78(5)"],"submitter":["Kowalski RG"],"pubmed_abstract":["<h4>Importance</h4>Traumatic brain injury (TBI) leads to 2.9 million visits to US emergency departments annually and frequently involves a disorder of consciousness (DOC). Early treatment, including withdrawal of life-sustaining therapies and rehabilitation, is often predicated on the assumed worse outcome of disrupted consciousness.<h4>Objective</h4>To quantify the loss of consciousness, factors associated with recovery, and return to functional independence in a 31-year sample of patients with moderate or severe brain trauma.<h4>Design, setting, and participants</h4>This cohort study analyzed patients with TBI who were enrolled in the Traumatic Brain Injury Model Systems National Database, a prospective, multiyear, longitudinal database. Patients were survivors of moderate or severe TBI "],"journal":["JAMA neurology"],"pagination":["548-557"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7922241"],"repository":["biostudies-literature"],"pubmed_title":["Recovery of Consciousness and Functional Outcome in Moderate and Severe Traumatic Brain Injury."],"pmcid":["PMC7922241"],"pubmed_authors":["Zafonte RD","Nakase-Richardson R","Whyte J","Hammond FM","Weintraub AH","Giacino JT","Kowalski RG"],"additional_accession":[]},"is_claimable":false,"name":"Recovery of Consciousness and Functional Outcome in Moderate and Severe Traumatic Brain Injury.","description":"<h4>Importance</h4>Traumatic brain injury (TBI) leads to 2.9 million visits to US emergency departments annually and frequently involves a disorder of consciousness (DOC). Early treatment, including withdrawal of life-sustaining therapies and rehabilitation, is often predicated on the assumed worse outcome of disrupted consciousness.<h4>Objective</h4>To quantify the loss of consciousness, factors associated with recovery, and return to functional independence in a 31-year sample of patients with moderate or severe brain trauma.<h4>Design, setting, and participants</h4>This cohort study analyzed patients with TBI who were enrolled in the Traumatic Brain Injury Model Systems National Database, a prospective, multiyear, longitudinal database. Patients were survivors of moderate or severe TBI ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 May","modification":"2026-06-12T10:27:03.292Z","creation":"2025-04-20T03:45:28.995Z"},"accession":"S-EPMC7922241","cross_references":{"pubmed":["33646273"],"doi":["10.1001/jamaneurol.2021.0084"]}}