biostudies-literatureUnknown3(1)Kukolja J<h4>Introduction</h4>Delirium is a frequent complication in hospitalised patients, often leading to difficulties in patient management and is associated with increased morbidity and mortality. Most patients in intensive care units develop delirium, however, it is also frequently observed in non-intensive care unit settings. Risk factors are, among others, older age, brain pathology, severe trauma, orthopaedic or heart surgery, metabolic or electrolyte dysregulations, infections and polypharmacy. The most important measures to prevent and treat delirium are recognition and removal of risk factors and causes. Although delirium is a very common and serious complication, evidence for pharmacological treatment is poor, and guidelines remain controversial. Accordingly, non-pharmacological treatmNeurological research and practice12https://www.ebi.ac.uk/biostudies/studies/S-EPMC7934272biostudies-literatureSOP: treatment of delirium.PMC7934272Kukolja JKuhn JfalseSOP: treatment of delirium.<h4>Introduction</h4>Delirium is a frequent complication in hospitalised patients, often leading to difficulties in patient management and is associated with increased morbidity and mortality. Most patients in intensive care units develop delirium, however, it is also frequently observed in non-intensive care unit settings. Risk factors are, among others, older age, brain pathology, severe trauma, orthopaedic or heart surgery, metabolic or electrolyte dysregulations, infections and polypharmacy. The most important measures to prevent and treat delirium are recognition and removal of risk factors and causes. Although delirium is a very common and serious complication, evidence for pharmacological treatment is poor, and guidelines remain controversial. Accordingly, non-pharmacological treatm2021-01-01T00:00:00Z2021 Mar2025-04-04T11:43:59.25Z2022-02-09T15:13:29.428ZS-EPMC79342723366359910.1186/s42466-021-00110-7