biostudies-literatureHossain PTakeda Pharmaceutical CompanyNovartise039209https://www.ebi.ac.uk/biostudies/studies/S-EPMC7934779biostudies-literatureUnknown11(3)<h4>Objectives</h4>To compare sociodemographics and vision-related quality of life (QoL) of individuals with or without dry eye disease (DED); and to explore the impact of DED symptom severity on visual function, activity limitations and work productivity.<h4>Design</h4>Cross-sectional web-based survey.<h4>Setting</h4>General UK population.<h4>Participants</h4>Adults ≥18 years with (N=1002) or without (N=1003) self-reported DED recruited through email and screened.<h4>Main outcome measures</h4>All participants completed the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25), with six additional questions (items A3-A8), and the EuroQol 5 dimensions 5 levels. DED participants also completed Impact of Dry Eye on Everyday Life questionnaire, 5-item Dry Eye Questionnaire BMJ openPatient-reported burden of dry eye disease in the UK: a cross-sectional web-based survey.PMC7934779N/ADana RMarkowitz JTJoseph CSiffel CHossain PMeunier JfalsePatient-reported burden of dry eye disease in the UK: a cross-sectional web-based survey.<h4>Objectives</h4>To compare sociodemographics and vision-related quality of life (QoL) of individuals with or without dry eye disease (DED); and to explore the impact of DED symptom severity on visual function, activity limitations and work productivity.<h4>Design</h4>Cross-sectional web-based survey.<h4>Setting</h4>General UK population.<h4>Participants</h4>Adults ≥18 years with (N=1002) or without (N=1003) self-reported DED recruited through email and screened.<h4>Main outcome measures</h4>All participants completed the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25), with six additional questions (items A3-A8), and the EuroQol 5 dimensions 5 levels. DED participants also completed Impact of Dry Eye on Everyday Life questionnaire, 5-item Dry Eye Questionnaire 2021-01-01T00:00:00Z2021 Mar2025-04-20T02:30:37.214Z2025-04-20T02:30:37.214ZS-EPMC79347793366406410.1136/bmjopen-2020-039209