{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["4(3)"],"submitter":["Brewster R"],"pubmed_abstract":["<h4>Importance</h4>Host-related immune factors have been implicated in the development and progression of diverse malignant neoplasms. Identifying associations between immunologic laboratory parameters and overall survival may inform novel prognostic biomarkers and mechanisms of antitumor immunity in localized bone and soft tissue sarcoma.<h4>Objective</h4>To assess whether lymphopenia at diagnosis is associated with overall survival among patients with localized bone and soft tissue sarcoma.<h4>Design, setting, and participants</h4>This retrospective cohort study analyzed patients from the Stanford Cancer Institute with localized bone and soft tissue sarcoma between September 1, 1998, and November 1, 2018. Patients were included if laboratory values were available within 60 days of diagno"],"journal":["JAMA network open"],"pagination":["e210845"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7936255"],"repository":["biostudies-literature"],"pubmed_title":["Evaluation of Absolute Lymphocyte Count at Diagnosis and Mortality Among Patients With Localized Bone or Soft Tissue Sarcoma."],"pmcid":["PMC7936255"],"pubmed_authors":["Wood D","Brewster R","Henry S","Purington N","Bui N","Ganjoo K"],"additional_accession":[]},"is_claimable":false,"name":"Evaluation of Absolute Lymphocyte Count at Diagnosis and Mortality Among Patients With Localized Bone or Soft Tissue Sarcoma.","description":"<h4>Importance</h4>Host-related immune factors have been implicated in the development and progression of diverse malignant neoplasms. Identifying associations between immunologic laboratory parameters and overall survival may inform novel prognostic biomarkers and mechanisms of antitumor immunity in localized bone and soft tissue sarcoma.<h4>Objective</h4>To assess whether lymphopenia at diagnosis is associated with overall survival among patients with localized bone and soft tissue sarcoma.<h4>Design, setting, and participants</h4>This retrospective cohort study analyzed patients from the Stanford Cancer Institute with localized bone and soft tissue sarcoma between September 1, 1998, and November 1, 2018. Patients were included if laboratory values were available within 60 days of diagno","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Mar","modification":"2025-04-20T02:27:06.973Z","creation":"2025-04-20T02:27:06.973Z"},"accession":"S-EPMC7936255","cross_references":{"pubmed":["33666664"],"doi":["10.1001/jamanetworkopen.2021.0845"]}}