{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mei S"],"funding":["National Natural Science Foundation of China"],"pagination":["8887244"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7936557"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["2021"],"pubmed_abstract":["The short tandem repeat (STR) loci are polymorphic markers in the combined DNA index system (CODIS) and non-CODIS STR loci. Due to the highly polymorphic characteristic of STR loci, they are popular and widely used in forensic DNA typing laboratories. In this study, 22 STR loci (1 CODIS, 21 non-CODIS STR loci) and an Amelogenin locus were genotyped and analyzed in 590 unrelated individuals of the Guanzhong Han population. None of the 22 STR loci deviated from the Hardy-Weinberg equilibrium, and all the loci were in the linkage equilibrium state. We observed 247 alleles, and the corresponding allelic frequencies ranged from 0.0008 to 0.3695 in the Guanzhong Han population. The combined power of discrimination and the cumulative exclusion probability was 0.999 999 999 999 999 999 999 999 999"],"journal":["BioMed research international"],"pubmed_title":["The Polymorphism Analyses of Short Tandem Repeats as a Basis for Understanding the Genetic Characteristics of the Guanzhong Han Population."],"pmcid":["PMC7936557"],"funding_grant_id":["8137248"],"pubmed_authors":["Liu Y","Zhao C","Li S","Mei S","Xu H","Zhu B"],"additional_accession":[]},"is_claimable":false,"name":"The Polymorphism Analyses of Short Tandem Repeats as a Basis for Understanding the Genetic Characteristics of the Guanzhong Han Population.","description":"The short tandem repeat (STR) loci are polymorphic markers in the combined DNA index system (CODIS) and non-CODIS STR loci. Due to the highly polymorphic characteristic of STR loci, they are popular and widely used in forensic DNA typing laboratories. In this study, 22 STR loci (1 CODIS, 21 non-CODIS STR loci) and an Amelogenin locus were genotyped and analyzed in 590 unrelated individuals of the Guanzhong Han population. None of the 22 STR loci deviated from the Hardy-Weinberg equilibrium, and all the loci were in the linkage equilibrium state. We observed 247 alleles, and the corresponding allelic frequencies ranged from 0.0008 to 0.3695 in the Guanzhong Han population. The combined power of discrimination and the cumulative exclusion probability was 0.999 999 999 999 999 999 999 999 999","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2025-04-05T13:48:53.715Z","creation":"2021-03-18T08:30:54Z"},"accession":"S-EPMC7936557","cross_references":{"pubmed":["33728348"],"doi":["10.1155/2021/8887244"]}}