biostudies-literatureAlwalid ONatural Science Foundation of Hubei Province619864https://www.ebi.ac.uk/biostudies/studies/S-EPMC7937935biostudies-literatureUnknown12<b>Background:</b> Intracranial aneurysm rupture is a devastating medical event with a high morbidity and mortality rate. Thus, timely detection and management are critical. The present study aimed to identify the aneurysm radiomics features associated with rupture and to build and evaluate a radiomics classification model of aneurysm rupture. <b>Methods:</b> Radiomics analysis was applied to CT angiography (CTA) images of 393 patients [152 (38.7%) with ruptured aneurysms]. Patients were divided at a ratio of 7:3 into retrospective training (<i>n</i> = 274) and prospective test (<i>n</i> = 119) cohorts. A total of 1,229 radiomics features were automatically calculated from each aneurysm. The feature number was systematically reduced, and the most important classifying features were selecteFrontiers in neurologyCT Angiography-Based Radiomics for Classification of Intracranial Aneurysm Rupture.PMC79379352019CFB297Cen CLiu HHan PYang JLong XXie MAlwalid OfalseCT Angiography-Based Radiomics for Classification of Intracranial Aneurysm Rupture.<b>Background:</b> Intracranial aneurysm rupture is a devastating medical event with a high morbidity and mortality rate. Thus, timely detection and management are critical. The present study aimed to identify the aneurysm radiomics features associated with rupture and to build and evaluate a radiomics classification model of aneurysm rupture. <b>Methods:</b> Radiomics analysis was applied to CT angiography (CTA) images of 393 patients [152 (38.7%) with ruptured aneurysms]. Patients were divided at a ratio of 7:3 into retrospective training (<i>n</i> = 274) and prospective test (<i>n</i> = 119) cohorts. A total of 1,229 radiomics features were automatically calculated from each aneurysm. The feature number was systematically reduced, and the most important classifying features were selecte2021-01-01T00:00:00Z20212025-04-04T08:31:34.514Z2021-03-12T08:17:23ZS-EPMC79379353369274110.3389/fneur.2021.619864