biostudies-literatureUnknown104(3)Moraleda CHoward Hughes Medical InstituteAnemia is a common condition in HIV-infected children; however, its pathophysiology and the contribution of frequent causes of anemia such as iron deficiency (ID) and malaria are poorly understood. We carried out an ancillary study on the effect of HIV on anemia as part of a case-control study on risk factors of anemia among Mozambican children aged 1-59 months with documented HIV status. Of them, 390 children were admitted to the hospital with anemia (hemoglobin [Hb] < 11 g/dL), whereas 272 children without anemia (Hb ≥ 11 g/dL) were recruited in the community. We assessed differences by HIV status in the presentation of anemia etiological factors and the effect of HIV infection on the association of each factor with anemia. Among the 99 HIV-infected and 563 uninfected children included, The American journal of tropical medicine and hygiene1003-1012https://www.ebi.ac.uk/biostudies/studies/S-EPMC7941855biostudies-literaturePathophysiology of Anemia in HIV-Infected Children Exposed to Malaria.PMC7941855Macete ERuperez MNhabomba AManu Pereira MDMMoraleda CAchtman AHSchofield LAguilar RMenendez CNhampossa TQuinto LAlonso PLRenom MAponte JJfalsePathophysiology of Anemia in HIV-Infected Children Exposed to Malaria.Anemia is a common condition in HIV-infected children; however, its pathophysiology and the contribution of frequent causes of anemia such as iron deficiency (ID) and malaria are poorly understood. We carried out an ancillary study on the effect of HIV on anemia as part of a case-control study on risk factors of anemia among Mozambican children aged 1-59 months with documented HIV status. Of them, 390 children were admitted to the hospital with anemia (hemoglobin [Hb] < 11 g/dL), whereas 272 children without anemia (Hb ≥ 11 g/dL) were recruited in the community. We assessed differences by HIV status in the presentation of anemia etiological factors and the effect of HIV infection on the association of each factor with anemia. Among the 99 HIV-infected and 563 uninfected children included, 2021-01-01T00:00:00Z2021 Jan2025-04-21T18:23:09.084Z2025-04-05T17:11:03.5ZS-EPMC79418553353475810.4269/ajtmh.19-0783