{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tang X"],"funding":["National Natural Science Foundation of China","The New Xiangya Talent Project of The Third Xiangya Hospital of Central South University"],"pagination":["42"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7942010"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(1)"],"pubmed_abstract":["Background
Endometriosis is a disease that involves active cell invasion and migration. Talin-1 can promote cell invasion, migration and adhension in various cancer cells, but its role in endometriosis has not been investigated. This study was to investigate the expression level of Talin-1 in endometriosis and the role of Talin-1 in the proliferation, adhesion, migration, and invasion of human endometrial stromal cells (ESCs).Methods
Ectopic and eutopic endometrial tissues were collected from women with endometriosis, and the control endometrial tissues were obtained from patients without endometriosis. The expression level of Talin-1 was detected in each sample using quantitative real-time polymerase chain reaction and immunohistochemistry. The expression of Talin-1 was in"],"journal":["Reproductive biology and endocrinology : RB&E"],"pubmed_title":["Expression of Talin-1 in endometriosis and its possible role in pathogenesis."],"pmcid":["PMC7942010"],"funding_grant_id":["No. JY201706","No. 81801422"],"pubmed_authors":["Jiang J","Li Q","Li L","Tang X"],"additional_accession":[]},"is_claimable":false,"name":"Expression of Talin-1 in endometriosis and its possible role in pathogenesis.","description":"Background
Endometriosis is a disease that involves active cell invasion and migration. Talin-1 can promote cell invasion, migration and adhension in various cancer cells, but its role in endometriosis has not been investigated. This study was to investigate the expression level of Talin-1 in endometriosis and the role of Talin-1 in the proliferation, adhesion, migration, and invasion of human endometrial stromal cells (ESCs).Methods
Ectopic and eutopic endometrial tissues were collected from women with endometriosis, and the control endometrial tissues were obtained from patients without endometriosis. The expression level of Talin-1 was detected in each sample using quantitative real-time polymerase chain reaction and immunohistochemistry. The expression of Talin-1 was in","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Mar","modification":"2025-04-21T18:11:14.77Z","creation":"2024-11-12T09:14:41.032Z"},"accession":"S-EPMC7942010","cross_references":{"pubmed":["33750407"],"doi":["10.1186/s12958-021-00725-0"]}}