{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["23(1)"],"submitter":["Miyawaki Y"],"pubmed_abstract":["<h4>Background</h4>While survival of systemic lupus erythematosus (SLE) patients has improved substantially, problems remain in the management of their emotional health. Medium to high-dose glucocorticoid doses are known to worsen emotional health; the effect is unclear among patients receiving relatively low-dose glucocorticoids. This study aims to investigate the association between low glucocorticoid doses and emotional health in lupus low disease activity state (LLDAS).<h4>Methods</h4>This cross-sectional study drew on data from SLE patients in 10 Japanese institutions. The participants were adult patients with SLE duration of ≥ 1 year who met LLDAS criteria at the study visit from April 2018 through September 2019. The exposure was the daily glucocorticoid dose (mg oral prednisolone)."],"journal":["Arthritis research & therapy"],"pagination":["79"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7944592"],"repository":["biostudies-literature"],"pubmed_title":["Association of glucocorticoid doses and emotional health in lupus low disease activity state (LLDAS): a cross-sectional study."],"pmcid":["PMC7944592"],"pubmed_authors":["Yoshimi R","Hiramatsu-Asano S","Fukuhara S","Katayama Y","Shimizu S","Ohashi K","Miyawaki Y","Yajima N","Ohno S","Watanabe H","Kajiyama H","Shimojima Y","Yamazaki H","Matsumoto Y","Wada J","Morishita M","Takano-Narazaki M","Ichinose K","Hayashi K","Ogawa Y","Sato S","Asano Y","Yamamura Y","Sada KE","Fujiwara M","Yamamoto Y"],"additional_accession":[]},"is_claimable":false,"name":"Association of glucocorticoid doses and emotional health in lupus low disease activity state (LLDAS): a cross-sectional study.","description":"<h4>Background</h4>While survival of systemic lupus erythematosus (SLE) patients has improved substantially, problems remain in the management of their emotional health. Medium to high-dose glucocorticoid doses are known to worsen emotional health; the effect is unclear among patients receiving relatively low-dose glucocorticoids. This study aims to investigate the association between low glucocorticoid doses and emotional health in lupus low disease activity state (LLDAS).<h4>Methods</h4>This cross-sectional study drew on data from SLE patients in 10 Japanese institutions. The participants were adult patients with SLE duration of ≥ 1 year who met LLDAS criteria at the study visit from April 2018 through September 2019. The exposure was the daily glucocorticoid dose (mg oral prednisolone).","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Mar","modification":"2025-04-18T16:41:39.204Z","creation":"2021-03-13T08:14:37Z"},"accession":"S-EPMC7944592","cross_references":{"pubmed":["33691746"],"doi":["10.1186/s13075-021-02466-2"]}}