biostudies-literatureBitarakwate EUnited States Agency for International Developmente0247507https://www.ebi.ac.uk/biostudies/studies/S-EPMC7946283biostudies-literatureUnknown16(3)<h4>Introduction</h4>The innovative Pratt pouch could optimize dispensing nevirapine prophylaxis to HIV-exposed infants in pre-measured single dose pouches to increase completion of the full 6 week infant nevirapine regimen.<h4>Materials and methods</h4>Nineteen health facilities with highest HIV positivity rates among pregnant women across 9 districts in southwest and central Uganda were assigned to control and intervention groups. HIV-positive women enrolled at intervention facilities received pouches filled with premeasured single doses of nevirapine using Uganda national guidelines, which were integrated into the existing drug distribution system. During antenatal care (ANC) women received 14 pouches to cover time until the 6 day postpartum visit, with an additional 8 pouches if women PloS oneEffects of the Pratt pouch model of dispensing nevirapine prophylaxis on HIV exposed infant completion of 6 weeks of prophylaxis in Uganda.PMC7946283Cooperative Agreement AID-OAA-A-16-00010Ashburn KKhamasi RNatumanya EOwomugisha BBitarakwate EKisaakye LKazooba PHerrera NMalkin RAfalseEffects of the Pratt pouch model of dispensing nevirapine prophylaxis on HIV exposed infant completion of 6 weeks of prophylaxis in Uganda.<h4>Introduction</h4>The innovative Pratt pouch could optimize dispensing nevirapine prophylaxis to HIV-exposed infants in pre-measured single dose pouches to increase completion of the full 6 week infant nevirapine regimen.<h4>Materials and methods</h4>Nineteen health facilities with highest HIV positivity rates among pregnant women across 9 districts in southwest and central Uganda were assigned to control and intervention groups. HIV-positive women enrolled at intervention facilities received pouches filled with premeasured single doses of nevirapine using Uganda national guidelines, which were integrated into the existing drug distribution system. During antenatal care (ANC) women received 14 pouches to cover time until the 6 day postpartum visit, with an additional 8 pouches if women 2021-01-01T00:00:00Z20212025-04-18T13:29:17.678Z2025-04-06T23:16:49.638ZS-EPMC79462833369061010.1371/journal.pone.0247507