{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(5)"],"submitter":["Giannini F"],"pubmed_abstract":["<h4>Background</h4>Coronavirus disease 2019 (COVID-19) has spread worldwide determining dramatic impacts on healthcare systems. Early identification of high-risk parameters is required in order to provide the best therapeutic approach. Coronary, thoracic aorta and aortic valve calcium can be measured from a non-gated chest computer tomography (CT) and are validated predictors of cardiovascular events and all-cause mortality. However, their prognostic role in acute systemic inflammatory diseases, such as COVID-19, has not been investigated.<h4>Objectives</h4>The aim was to evaluate the association of coronary artery calcium and total thoracic calcium on in-hospital mortality in COVID-19 patients.<h4>Methods</h4>1093 consecutive patients from 16 Italian hospitals with a positive swab for COV"],"journal":["Journal of cardiovascular computed tomography"],"pagination":["421-430"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7946543"],"repository":["biostudies-literature"],"pubmed_title":["Coronary and total thoracic calcium scores predict mortality and provides pathophysiologic insights in COVID-19 patients."],"pmcid":["PMC7946543"],"pubmed_authors":["Costa C","Cesini E","Scarnecchia E","Baffoni L","Gnasso C","Iacovoni A","Giannini F","Cereda A","Bonaffini PA","Leone R","Pacielli A","Besana F","Ferrari R","Esposito A","Senni M","Colombo A","Vignali L","Sironi S","Fominskiy E","Micossi C","Sperandio M","Bellani G","Danzi GB","Vaudano PG","Mancini EM","Pontone G","Vignale D","Benatti G","Boccia E","De Carlini CC","Loffi M","Andreini D","Maggiolini S","Tacchetti C","Palmisano A","Anastasio F","Toselli M","Rapezzi C","Iannaccone M","Patelli G","Manfrini M","Iannopollo G","Biagi A","Turchio P","Monello A","Khokhar A","Spreafico C","Casella G","Ippolito D","Landoni G","Nicoletti V","De Cobelli F","Muri M","Campo G","Ponticelli F","Nannini T","Maggioni AP","Sticchi A","Sverzellati N","Gardi I","Scoccia A","Franzesi CT","Lombardo FP"],"additional_accession":[]},"is_claimable":false,"name":"Coronary and total thoracic calcium scores predict mortality and provides pathophysiologic insights in COVID-19 patients.","description":"<h4>Background</h4>Coronavirus disease 2019 (COVID-19) has spread worldwide determining dramatic impacts on healthcare systems. Early identification of high-risk parameters is required in order to provide the best therapeutic approach. Coronary, thoracic aorta and aortic valve calcium can be measured from a non-gated chest computer tomography (CT) and are validated predictors of cardiovascular events and all-cause mortality. However, their prognostic role in acute systemic inflammatory diseases, such as COVID-19, has not been investigated.<h4>Objectives</h4>The aim was to evaluate the association of coronary artery calcium and total thoracic calcium on in-hospital mortality in COVID-19 patients.<h4>Methods</h4>1093 consecutive patients from 16 Italian hospitals with a positive swab for COV","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep-Oct","modification":"2025-04-04T08:31:42.963Z","creation":"2021-03-14T08:21:24Z"},"accession":"S-EPMC7946543","cross_references":{"pubmed":["33744175"],"doi":["10.1016/j.jcct.2021.03.003"]}}