biostudies-literatureUnknown15(5)Giannini F<h4>Background</h4>Coronavirus disease 2019 (COVID-19) has spread worldwide determining dramatic impacts on healthcare systems. Early identification of high-risk parameters is required in order to provide the best therapeutic approach. Coronary, thoracic aorta and aortic valve calcium can be measured from a non-gated chest computer tomography (CT) and are validated predictors of cardiovascular events and all-cause mortality. However, their prognostic role in acute systemic inflammatory diseases, such as COVID-19, has not been investigated.<h4>Objectives</h4>The aim was to evaluate the association of coronary artery calcium and total thoracic calcium on in-hospital mortality in COVID-19 patients.<h4>Methods</h4>1093 consecutive patients from 16 Italian hospitals with a positive swab for COVJournal of cardiovascular computed tomography421-430https://www.ebi.ac.uk/biostudies/studies/S-EPMC7946543biostudies-literatureCoronary and total thoracic calcium scores predict mortality and provides pathophysiologic insights in COVID-19 patients.PMC7946543Costa CCesini EScarnecchia EBaffoni LGnasso CIacovoni AGiannini FCereda ABonaffini PALeone RPacielli ABesana FFerrari REsposito ASenni MColombo AVignali LSironi SFominskiy EMicossi CSperandio MBellani GDanzi GBVaudano PGMancini EMPontone GVignale DBenatti GBoccia EDe Carlini CCLoffi MAndreini DMaggiolini STacchetti CPalmisano AAnastasio FToselli MRapezzi CIannaccone MPatelli GManfrini MIannopollo GBiagi ATurchio PMonello AKhokhar ASpreafico CCasella GIppolito DLandoni GNicoletti VDe Cobelli FMuri MCampo GPonticelli FNannini TMaggioni APSticchi ASverzellati NGardi IScoccia AFranzesi CTLombardo FPfalseCoronary and total thoracic calcium scores predict mortality and provides pathophysiologic insights in COVID-19 patients.<h4>Background</h4>Coronavirus disease 2019 (COVID-19) has spread worldwide determining dramatic impacts on healthcare systems. Early identification of high-risk parameters is required in order to provide the best therapeutic approach. Coronary, thoracic aorta and aortic valve calcium can be measured from a non-gated chest computer tomography (CT) and are validated predictors of cardiovascular events and all-cause mortality. However, their prognostic role in acute systemic inflammatory diseases, such as COVID-19, has not been investigated.<h4>Objectives</h4>The aim was to evaluate the association of coronary artery calcium and total thoracic calcium on in-hospital mortality in COVID-19 patients.<h4>Methods</h4>1093 consecutive patients from 16 Italian hospitals with a positive swab for COV2021-01-01T00:00:00Z2021 Sep-Oct2025-04-04T08:31:42.963Z2021-03-14T08:21:24ZS-EPMC79465433374417510.1016/j.jcct.2021.03.003