biostudies-literatureStevens ELNHLBI NIH HHSNIMHD NIH HHSNational Institutes of Health1319-1326.e3https://www.ebi.ac.uk/biostudies/studies/S-EPMC7946650biostudies-literatureUnknown9(3)<h4>Background</h4>Maternal depression has been linked to health care use for asthma in cross-sectional or short-term follow-up studies of school-aged children.<h4>Objective</h4>To examine whether increased or persistent maternal depressive symptoms over approximately 5 years are associated with severe asthma exacerbations or worse lung function in youth.<h4>Methods</h4>A prospective study of 386 youth living in Puerto Rico, aged 6 to 14 years at a baseline visit and 9 to 20 years at a second visit, was performed. Our exposure of interest was change in persistence of maternal depressive symptoms, assessed at both visits using the Center for Epidemiologic Studies Depression Scale (CESD). Our outcomes of interest were change in percent predicted forced expiratory volume in 1 second (FEV<sub>The journal of allergy and clinical immunology. In practiceMaternal Depressive Symptoms, Lung Function, and Severe Asthma Exacerbations in Puerto Rican Children.PMC7946650R01 MD011764T32 HL129949R01 HL079966R01 HL117191Celedon JCRosser FMiller GEAcosta-Perez EForno ECanino GStevens ELHan YYfalseMaternal Depressive Symptoms, Lung Function, and Severe Asthma Exacerbations in Puerto Rican Children.<h4>Background</h4>Maternal depression has been linked to health care use for asthma in cross-sectional or short-term follow-up studies of school-aged children.<h4>Objective</h4>To examine whether increased or persistent maternal depressive symptoms over approximately 5 years are associated with severe asthma exacerbations or worse lung function in youth.<h4>Methods</h4>A prospective study of 386 youth living in Puerto Rico, aged 6 to 14 years at a baseline visit and 9 to 20 years at a second visit, was performed. Our exposure of interest was change in persistence of maternal depressive symptoms, assessed at both visits using the Center for Epidemiologic Studies Depression Scale (CESD). Our outcomes of interest were change in percent predicted forced expiratory volume in 1 second (FEV<sub>2021-01-01T00:00:00Z2021 Mar2025-04-04T19:53:58.73Z2025-04-04T19:53:58.73ZS-EPMC79466503312752110.1016/j.jaip.2020.10.023