{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["23(2)"],"submitter":["Li G"],"pubmed_abstract":["<h4>Background</h4>The gut microbiome is receiving considerable attention as a potentially modifiable risk factor and therapeutic target for numerous mental and neurological diseases.<h4>Objective</h4>This study aimed to explore and assess the difference in the composition of gut microbes and fecal metabolites between women with hypoactive sexual desire disorder (HSDD) and healthy controls.<h4>Methods</h4>We employed an online recruitment method to enroll \"hard-to-reach\" HSDD populations. After a stringent diagnostic and exclusion process based on DSM-IV criteria, fecal samples collected from 24 women with HSDD and 22 age-matched, healthy controls underwent microbiome analysis using 16S ribosomal RNA gene sequencing and metabolome analysis using untargeted liquid chromatography-mass spectr"],"journal":["Journal of medical Internet research"],"pagination":["e25342"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7952237"],"repository":["biostudies-literature"],"pubmed_title":["Differences in the Gut Microbiome of Women With and Without Hypoactive Sexual Desire Disorder: Case Control Study."],"pmcid":["PMC7952237"],"pubmed_authors":["Li G","Shen Q","Zhou P","Song B","Wang C","Xu C","Wang G","Tang D","Wei Z","Wu H","Li W","Geng H","Zhang Z","He X","Cao Y","Gao Y","Li B","Xu X"],"additional_accession":[]},"is_claimable":false,"name":"Differences in the Gut Microbiome of Women With and Without Hypoactive Sexual Desire Disorder: Case Control Study.","description":"<h4>Background</h4>The gut microbiome is receiving considerable attention as a potentially modifiable risk factor and therapeutic target for numerous mental and neurological diseases.<h4>Objective</h4>This study aimed to explore and assess the difference in the composition of gut microbes and fecal metabolites between women with hypoactive sexual desire disorder (HSDD) and healthy controls.<h4>Methods</h4>We employed an online recruitment method to enroll \"hard-to-reach\" HSDD populations. After a stringent diagnostic and exclusion process based on DSM-IV criteria, fecal samples collected from 24 women with HSDD and 22 age-matched, healthy controls underwent microbiome analysis using 16S ribosomal RNA gene sequencing and metabolome analysis using untargeted liquid chromatography-mass spectr","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Feb","modification":"2025-04-18T16:41:14.003Z","creation":"2025-04-07T04:04:47.574Z"},"accession":"S-EPMC7952237","cross_references":{"pubmed":["33629964"],"doi":["10.2196/25342"]}}