biostudies-literatureReddiess PSwiss National Science FoundationE117-E123https://www.ebi.ac.uk/biostudies/studies/S-EPMC7954562biostudies-literatureUnknown193(4)<h4>Background</h4>Little is known about the association between alcohol consumption and risk of cardiovascular events in patients with established atrial fibrillation (AF). The main aim of the current study was to investigate the associations of regular alcohol intake with incident stroke or systemic embolism in patients with established AF.<h4>Methods</h4>To assess the association between alcohol consumption and cardiovascular events in patients with established AF, we combined data from 2 comparable prospective cohort studies that followed 3852 patients with AF for a median of 3.0 years. Patients were grouped into 4 categories of daily alcohol intake (none, > 0 to < 1, 1 to < 2 and ≥ 2 drinks/d). The primary outcome was a composite of stroke and systemic embolism. Secondary outcomes werCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienneAlcohol consumption and risk of cardiovascular outcomes and bleeding in patients with established atrial fibrillation.PMC7954562148474159322Reddiess PCoslovsky MSteiner FKuhne MDi Valentino MConen DBaretella OOsswald SBonati LHAeschbacher SKobza RSticherling CMeyre PBEAT-AF and Swiss-AF investigatorsBeer JHMuller CMoschovitis GRodondi NfalseAlcohol consumption and risk of cardiovascular outcomes and bleeding in patients with established atrial fibrillation.<h4>Background</h4>Little is known about the association between alcohol consumption and risk of cardiovascular events in patients with established atrial fibrillation (AF). The main aim of the current study was to investigate the associations of regular alcohol intake with incident stroke or systemic embolism in patients with established AF.<h4>Methods</h4>To assess the association between alcohol consumption and cardiovascular events in patients with established AF, we combined data from 2 comparable prospective cohort studies that followed 3852 patients with AF for a median of 3.0 years. Patients were grouped into 4 categories of daily alcohol intake (none, > 0 to < 1, 1 to < 2 and ≥ 2 drinks/d). The primary outcome was a composite of stroke and systemic embolism. Secondary outcomes wer2021-01-01T00:00:00Z2021 Jan2025-04-25T19:29:31.464Z2025-04-06T07:57:59.176ZS-EPMC79545623366718010.1503/cmaj.200778