biostudies-literatureLeow KNIAMS NIH HHSe017205https://www.ebi.ac.uk/biostudies/studies/S-EPMC7955302biostudies-literatureUnknown10(2)Background The prognostic importance of abdominal aortic calcification (AAC) viewed on noninvasive imaging modalities remains uncertain. Methods and Results We searched electronic databases (MEDLINE and Embase) until March 2018. Multiple reviewers identified prospective studies reporting AAC and incident cardiovascular events or all-cause mortality. Two independent reviewers assessed eligibility and risk of bias and extracted data. Summary risk ratios (RRs) were estimated using random-effects models comparing the higher AAC groups combined (any or more advanced AAC) to the lowest reported AAC group. We identified 52 studies (46 cohorts, 36 092 participants); only studies of patients with chronic kidney disease (57%) and the general older-elderly (median, 68 years; range, 60-80 years) populJournal of the American Heart AssociationPrognostic Value of Abdominal Aortic Calcification: A Systematic Review and Meta-Analysis of Observational Studies.PMC7955302R01 AR041398Schousboe JTSzulc PKiel DPSim MBondonno NSawang MShaikh HLim WHHodgson JMSharma ATeixeira-Pinto AThompson PLCraig JCLewis JRPrince RLWong GLeow KfalsePrognostic Value of Abdominal Aortic Calcification: A Systematic Review and Meta-Analysis of Observational Studies.Background The prognostic importance of abdominal aortic calcification (AAC) viewed on noninvasive imaging modalities remains uncertain. Methods and Results We searched electronic databases (MEDLINE and Embase) until March 2018. Multiple reviewers identified prospective studies reporting AAC and incident cardiovascular events or all-cause mortality. Two independent reviewers assessed eligibility and risk of bias and extracted data. Summary risk ratios (RRs) were estimated using random-effects models comparing the higher AAC groups combined (any or more advanced AAC) to the lowest reported AAC group. We identified 52 studies (46 cohorts, 36 092 participants); only studies of patients with chronic kidney disease (57%) and the general older-elderly (median, 68 years; range, 60-80 years) popul2021-01-01T00:00:00Z2021 Jan2025-04-04T21:16:03.28Z2025-04-04T21:16:03.28ZS-EPMC79553023343967210.1161/JAHA.120.017205