biostudies-literatureSaeed ONCATS NIH HHSNHLBI NIH HHSe018475https://www.ebi.ac.uk/biostudies/studies/S-EPMC7955378biostudies-literatureUnknown9(24)Background Severe coronavirus disease 2019 (COVID-19) is characterized by a proinflammatory state with high mortality. Statins have anti-inflammatory effects and may attenuate the severity of COVID-19. Methods and Results An observational study of all consecutive adult patients with COVID-19 admitted to a single center located in Bronx, New York, was conducted from March 1, 2020, to May 2, 2020. Patients were grouped as those who did and those who did not receive a statin, and in-hospital mortality was compared by competing events regression. In addition, propensity score matching and inverse probability treatment weighting were used in survival models to examine the association between statin use and death during hospitalization. A total of 4252 patients were admitted with COVID-19. DiabeJournal of the American Heart AssociationStatin Use and In-Hospital Mortality in Patients With Diabetes Mellitus and COVID-19.PMC7955378K23 HL145140UL1 TR002556UL1 TR001073Sims DBSaeed OGarcia MJXue XAlvarez CRochlani YJorde UPAgalliu IKataria RPatel SRRivas-Lasarte MCastagna FVukelic SfalseStatin Use and In-Hospital Mortality in Patients With Diabetes Mellitus and COVID-19.Background Severe coronavirus disease 2019 (COVID-19) is characterized by a proinflammatory state with high mortality. Statins have anti-inflammatory effects and may attenuate the severity of COVID-19. Methods and Results An observational study of all consecutive adult patients with COVID-19 admitted to a single center located in Bronx, New York, was conducted from March 1, 2020, to May 2, 2020. Patients were grouped as those who did and those who did not receive a statin, and in-hospital mortality was compared by competing events regression. In addition, propensity score matching and inverse probability treatment weighting were used in survival models to examine the association between statin use and death during hospitalization. A total of 4252 patients were admitted with COVID-19. Diabe2020-01-01T00:00:00Z2020 Dec2025-04-22T10:43:50.027Z2025-04-05T23:41:26.938ZS-EPMC79553783309244610.1161/JAHA.120.018475