biostudies-literatureUnknown10(1)Van Spall HGCCIHRBackground Patients with chronic disease prefer an adequately supported death at home, but often die in the hospital. We assessed temporal trends and sex differences in healthcare intensity and location of death among decedents with heart failure. Methods and Results This was a retrospective cohort study of adults with heart failure who died between April 1, 2004 and March 31, 2017 in Ontario, Canada. We used population-based administrative databases to assess healthcare utilization during the last 6 months of life and applied multilevel multivariable logistic regression to assess whether sex was independently associated with location of death. Among 396 024 decedents with heart failure, mean (SD) age was 81.8 (10.7) years, 51.5% were women, and 53.4% had in-hospital deaths. From 2004 to 2Journal of the American Heart Associatione018495https://www.ebi.ac.uk/biostudies/studies/S-EPMC7955486biostudies-literatureTemporal Trends and Sex Differences in Intensity of Healthcare at the End of Life in Adults With Heart Failure.PMC7955486Hill ADRoss HJVan Spall HGCFowler RAFu LfalseTemporal Trends and Sex Differences in Intensity of Healthcare at the End of Life in Adults With Heart Failure.Background Patients with chronic disease prefer an adequately supported death at home, but often die in the hospital. We assessed temporal trends and sex differences in healthcare intensity and location of death among decedents with heart failure. Methods and Results This was a retrospective cohort study of adults with heart failure who died between April 1, 2004 and March 31, 2017 in Ontario, Canada. We used population-based administrative databases to assess healthcare utilization during the last 6 months of life and applied multilevel multivariable logistic regression to assess whether sex was independently associated with location of death. Among 396 024 decedents with heart failure, mean (SD) age was 81.8 (10.7) years, 51.5% were women, and 53.4% had in-hospital deaths. From 2004 to 22021-01-01T00:00:00Z2021 Jan2025-04-18T16:41:52.23Z2025-04-07T04:07:05.327ZS-EPMC79554863332524910.1161/JAHA.120.018495