biostudies-literatureUnknown10(1)Kodani EBackground Blood pressure (BP) variability has reportedly been a risk factor for various clinical events. To clarify the influence of BP visit-to-visit variability on adverse events in patients with nonvalvular atrial fibrillation, a post hoc analysis of the J-RHYTHM Registry was performed. Methods and Results Of 7406 outpatients with nonvalvular atrial fibrillation from 158 institutions, 7226 (age, 69.7±9.9 years; men, 70.7%), in whom BP was measured 4 times or more (14.6±5.0 times) during the 2-year follow-up period or until occurrence of an event, constituted the study group. SD and coefficient of variation of BP values were calculated as BP variability. Thromboembolism, major hemorrhage, and all-cause death occurred in 110 (1.5%), 121 (1.7%), and 168 (2.3%) patients, respectively. WhenJournal of the American Heart Associatione018585https://www.ebi.ac.uk/biostudies/studies/S-EPMC7955501biostudies-literatureImpact of Blood Pressure Visit-to-Visit Variability on Adverse Events in Patients With Nonvalvular Atrial Fibrillation: Subanalysis of the J-RHYTHM Registry.PMC7955501Kumagai KArakawa TSukekawa HSaito MYamashiro KKawamura YWatanabe EWatanabe IKanda KYoshiga YAjiki KOtsuka TAzegami KUchida MYamazaki MDoi YYamashina AAizawa YInoue HKoretsune YOrigasa HYamanouchi YTsunoda YYamada YMoritani HSawanobori TKageyama SMakino NYamasaki JSugi KSakurada HSatoh TAtarashi HSohara HHigashi YFukuizumi YAoki MKaneko YHonda HImamura YOgino TOhta MUrushida TYamabe HImamura TNomura MYamashita TOkuyama YSato MTsuboi NIwao TTakagi YKubota TKanki HMine TSugiyama KEbe KMorishima ITakagi MNagahori WSadamatsu KFujiu KKitahara YKubota IHirayama HAkizawa MMurakawa YKurita TUeno HYamawake NKojima THirayama YMurasaki KTatsuno HOsanai HNakada SSakabe MIkeda TSugiura AIkeda KItoh TWatarai MKobori AKawano YOsaka TSakurai MItoh MFukamizu SHirose TSakurai KNakamura TMitamura HAmino MNiwano SHayami NAbe YIshiyama TSuzuki MIzawa HOkishige KNakata AOguma MSuzuki HSatomi KMaemura KTakami KYagi THagiwara NShibayama KWatanabe TSawaguchi MAndo SFurushima HYamauchi MHarada SFukatani MOnodera TNishikado ATomita TUeda YHarada MOkawa MSagara KKonta YNishida KHayashi HObata HOkubo SMakita TOkubo TKusano KOgawa HShimada KKinbara TTerata KImai YMorikawa MMurohara TKatoh TKanaya TTokunaga TNakazato YKamiyama YIgawa OMaki TSoeki TKuboyama OOgawa SIchikawa MOgawa MHatayama THamada TKimura KOoie TKimura MTanaka YHirono OAdachi MTanaka NSaikawa TKodani EEguma HIkeuchi MOkumura KAsanoi HAoyagi HToratani NOhte NChishaki AYoshida HTagawa MYoshida KBando STakechi MYoshida YUrabe YJ‐RHYTHM Registry Investigators *Hayano TFujii EHirata AMotoki KIto MMiyanaga SInou TGoto TMitsuke YTakano MTachibana HUmeda YIto HHayano MKomiya NKaname NYamamoto KTakada YYano AYagishita AKomatsu TYamamoto TSaku KHirao KYoshioka KEndo YNoda TIshida AKodama INishizaki MKijima YShimizu HKato JShimizu AKato NYusu STakahashi NSumiyoshi MMizuno HTange SKamakura SManita MOhkubo KTakeda NSeo HHiguchi YKato RLeeInden YKitamura KMatsuura TNarita SKitamura SKamiya HMatsumoto KKobayashi YNakagawa SMatsumoto IOzawa TOkada SSenga MHaruna TMatsumoto NfalseImpact of Blood Pressure Visit-to-Visit Variability on Adverse Events in Patients With Nonvalvular Atrial Fibrillation: Subanalysis of the J-RHYTHM Registry.Background Blood pressure (BP) variability has reportedly been a risk factor for various clinical events. To clarify the influence of BP visit-to-visit variability on adverse events in patients with nonvalvular atrial fibrillation, a post hoc analysis of the J-RHYTHM Registry was performed. Methods and Results Of 7406 outpatients with nonvalvular atrial fibrillation from 158 institutions, 7226 (age, 69.7±9.9 years; men, 70.7%), in whom BP was measured 4 times or more (14.6±5.0 times) during the 2-year follow-up period or until occurrence of an event, constituted the study group. SD and coefficient of variation of BP values were calculated as BP variability. Thromboembolism, major hemorrhage, and all-cause death occurred in 110 (1.5%), 121 (1.7%), and 168 (2.3%) patients, respectively. When2021-01-01T00:00:00Z2021 Jan2025-04-22T10:51:28.77Z2025-04-05T23:40:39.002ZS-EPMC79555013337254110.1161/JAHA.120.018585