biostudies-literatureUnknown38(4)McGuinness BJIntradural extramedullary foramen magnum enhancing lesions may be due to meningioma, nerve sheath tumor, aneurysm, or meningeal disease. In this clinical report of 14 patients, we describe a novel imaging finding within the foramen magnum that simulates disease. The lesion is hyperintense on 3D-FLAIR and enhances on 3D gradient-echo sequences but is not seen on 2D-TSE T2WI. It occurs at a characteristic location related to the posterior aspect of the intradural vertebral artery just distal to the dural penetration. Stability of this lesion was demonstrated in those patients who underwent follow-up imaging. Recognition of this apparently benign lesion may prevent unnecessary patient anxiety and repeat imaging.AJNR. American journal of neuroradiology721-725https://www.ebi.ac.uk/biostudies/studies/S-EPMC7960232biostudies-literatureBenign Enhancing Foramen Magnum Lesions: Clinical Report of a Newly Recognized Entity.PMC7960232Morrison JPMcGuinness BJMoriarty MWBrew SKfalseBenign Enhancing Foramen Magnum Lesions: Clinical Report of a Newly Recognized Entity.Intradural extramedullary foramen magnum enhancing lesions may be due to meningioma, nerve sheath tumor, aneurysm, or meningeal disease. In this clinical report of 14 patients, we describe a novel imaging finding within the foramen magnum that simulates disease. The lesion is hyperintense on 3D-FLAIR and enhances on 3D gradient-echo sequences but is not seen on 2D-TSE T2WI. It occurs at a characteristic location related to the posterior aspect of the intradural vertebral artery just distal to the dural penetration. Stability of this lesion was demonstrated in those patients who underwent follow-up imaging. Recognition of this apparently benign lesion may prevent unnecessary patient anxiety and repeat imaging.2017-01-01T00:00:00Z2017 Apr2025-04-05T15:26:18.522Z2025-04-05T15:26:18.522ZS-EPMC79602322815412410.3174/ajnr.a508510.3174/ajnr.A5085