biostudies-literatureUnknown38(5)Brinjikji W<h4>Background and purpose</h4>Among patients with vertebrobasilar dolichoectasia is a subset of patients with disease affecting the anterior circulation as well. We hypothesized that multivessel intracranial dolichoectasia may represent a distinct phenotype from single-territory vertebrobasilar dolichoectasia. The purpose of this study was to characterize clinical characteristics and angiographic features of this proposed distinct phenotype termed "diffuse intracranial dolichoectasia" and compare them with those in patients with isolated vertebrobasilar dolichoectasia.<h4>Materials and methods</h4>We retrospectively reviewed a consecutive series of patients with diffuse intracranial dolichoectasia and compared their demographics, vascular risk factors, additional aneurysm prevalence, and AJNR. American journal of neuroradiology915-922https://www.ebi.ac.uk/biostudies/studies/S-EPMC7960370biostudies-literatureClinical and Imaging Characteristics of Diffuse Intracranial Dolichoectasia.PMC7960370Flemming KDNasr DMCloft HJBrinjikji WLanzino GKallmes DFRouchaud AfalseClinical and Imaging Characteristics of Diffuse Intracranial Dolichoectasia.<h4>Background and purpose</h4>Among patients with vertebrobasilar dolichoectasia is a subset of patients with disease affecting the anterior circulation as well. We hypothesized that multivessel intracranial dolichoectasia may represent a distinct phenotype from single-territory vertebrobasilar dolichoectasia. The purpose of this study was to characterize clinical characteristics and angiographic features of this proposed distinct phenotype termed "diffuse intracranial dolichoectasia" and compare them with those in patients with isolated vertebrobasilar dolichoectasia.<h4>Materials and methods</h4>We retrospectively reviewed a consecutive series of patients with diffuse intracranial dolichoectasia and compared their demographics, vascular risk factors, additional aneurysm prevalence, and 2017-01-01T00:00:00Z2017 May2025-04-05T15:26:07.813Z2025-04-05T15:26:07.813ZS-EPMC79603702825503210.3174/ajnr.A510210.3174/ajnr.a5102