{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Guo H"],"funding":["UC Berkeley Superfund Research Program"],"pubmed_abstract":["Recent evidence has accumulated that the immune system is intimately intertwined with cancer development. Two key characteristics of carcinogens in which the immune system plays a central role are chronic inflammation and immunosuppression. In this systematic review, we investigated the association of chronic inflammatory and immunosuppressive outcomes with benzene, a widely used industrial chemical. Benzene has been confirmed to cause acute myeloid leukaemia and suspected to cause non-Hodgkin lymphoma, two cancers of the blood-forming system that affect immune cells. We systematically searched PubMed and Embase for all relevant studies using a combination of Medical Subject Headings (MeSH) and selected key words. The detailed review protocol, including search strategy, was registered with"],"journal":["Occupational and environmental medicine"],"pagination":["oemed-2020-106517"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7960562"],"repository":["biostudies-literature"],"pubmed_title":["Benzene-associated immunosuppression and chronic inflammation in humans: a systematic review."],"pmcid":["PMC7960562"],"funding_grant_id":["P42ES004705"],"pubmed_authors":["Guo H","Zhang L","Ahn S"],"additional_accession":[]},"is_claimable":false,"name":"Benzene-associated immunosuppression and chronic inflammation in humans: a systematic review.","description":"Recent evidence has accumulated that the immune system is intimately intertwined with cancer development. Two key characteristics of carcinogens in which the immune system plays a central role are chronic inflammation and immunosuppression. In this systematic review, we investigated the association of chronic inflammatory and immunosuppressive outcomes with benzene, a widely used industrial chemical. Benzene has been confirmed to cause acute myeloid leukaemia and suspected to cause non-Hodgkin lymphoma, two cancers of the blood-forming system that affect immune cells. We systematically searched PubMed and Embase for all relevant studies using a combination of Medical Subject Headings (MeSH) and selected key words. The detailed review protocol, including search strategy, was registered with","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Sep","modification":"2025-04-18T12:20:08.223Z","creation":"2025-04-06T21:53:57.661Z"},"accession":"S-EPMC7960562","cross_references":{"pubmed":["32938756"],"doi":["10.1136/oemed-2020-106517"]}}