{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Wang Q"],"funding":["National Institute of Food and Agriculture","Alabama Agricultural Experiment Station"],"pubmed_abstract":["Reactive oxygen species (ROS) produced by hosts serve as a general defense mechanism against various pathogens. At the interaction site between the host and pathogen, host cells rapidly accumulate high concentrations of ROS, called the oxidative burst, that damage and kill the invading microbes. However, successful pathogens usually survive in a high ROS environment and have evolved strategies to overcome these detrimental effects. Here we characterized the biological function of the extracellular superoxide dismutase (SOD) FoSod5 from <i>Fusarium oxysporum</i> f. sp. <i>vasinfectum</i>. <i>FoSOD5</i> is strongly up-regulated during infection of cotton, and a Δ<i>FoSOD5</i> mutant was significantly reduced in virulence on cotton. Purified 6 × His-FoSod5 could significantly inhibit the redu"],"journal":["Frontiers in plant science"],"pagination":["608861"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7960929"],"repository":["biostudies-literature"],"pubmed_title":["The Extracellular Superoxide Dismutase Sod5 From <i>Fusarium oxysporum</i> Is Localized in Response to External Stimuli and Contributes to Fungal Pathogenicity."],"pmcid":["PMC7960929"],"pubmed_authors":["Pokhrel A","Wang Q","Coleman JJ"],"additional_accession":[]},"is_claimable":false,"name":"The Extracellular Superoxide Dismutase Sod5 From <i>Fusarium oxysporum</i> Is Localized in Response to External Stimuli and Contributes to Fungal Pathogenicity.","description":"Reactive oxygen species (ROS) produced by hosts serve as a general defense mechanism against various pathogens. At the interaction site between the host and pathogen, host cells rapidly accumulate high concentrations of ROS, called the oxidative burst, that damage and kill the invading microbes. However, successful pathogens usually survive in a high ROS environment and have evolved strategies to overcome these detrimental effects. Here we characterized the biological function of the extracellular superoxide dismutase (SOD) FoSod5 from <i>Fusarium oxysporum</i> f. sp. <i>vasinfectum</i>. <i>FoSOD5</i> is strongly up-regulated during infection of cotton, and a Δ<i>FoSOD5</i> mutant was significantly reduced in virulence on cotton. Purified 6 × His-FoSod5 could significantly inhibit the redu","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2025-04-22T10:50:04.79Z","creation":"2025-04-05T23:40:13.132Z"},"accession":"S-EPMC7960929","cross_references":{"pubmed":["33737941"],"doi":["10.3389/fpls.2021.608861"]}}