biostudies-literatureUnknown12Metayer-Coustard SIn chickens, a divergent selection on the <i>Pectoralis major</i> pHu allowed the creation of the pHu+ and pHu- lines, which represent a unique model for studying the biological control of carbohydrate storage in muscle. The present study aimed to describe the early mechanisms involved in the establishment of pHu+ and pHu- phenotypes. At hatching, pHu+ chicks were slightly heavier but exhibited lower plasma glucose and triglyceride and higher uric acid. After 5 days, pHu+ chicks exhibited higher breast meat yield compared to pHu- while their body weight was no different. At both ages, <i>in vivo</i> muscle glycogen content was lower in pHu+ than in pHu- muscles. The lower ability of pHu+ chicks to store carbohydrate in their muscle was associated with the increased expression of <i>SLC2A1<Frontiers in physiology643580https://www.ebi.ac.uk/biostudies/studies/S-EPMC7969813biostudies-literatureEarly Growth and Protein-Energy Metabolism in Chicken Lines Divergently Selected on Ultimate pH.PMC7969813Tesseraud SBordeau TCailleau-Audouin EGodet EDelaveau JMetayer-Coustard SPraud CBerri CRoyer DCoudert ELe Bihan-Duval EfalseEarly Growth and Protein-Energy Metabolism in Chicken Lines Divergently Selected on Ultimate pH.In chickens, a divergent selection on the <i>Pectoralis major</i> pHu allowed the creation of the pHu+ and pHu- lines, which represent a unique model for studying the biological control of carbohydrate storage in muscle. The present study aimed to describe the early mechanisms involved in the establishment of pHu+ and pHu- phenotypes. At hatching, pHu+ chicks were slightly heavier but exhibited lower plasma glucose and triglyceride and higher uric acid. After 5 days, pHu+ chicks exhibited higher breast meat yield compared to pHu- while their body weight was no different. At both ages, <i>in vivo</i> muscle glycogen content was lower in pHu+ than in pHu- muscles. The lower ability of pHu+ chicks to store carbohydrate in their muscle was associated with the increased expression of <i>SLC2A1<2021-01-01T00:00:00Z20212025-04-22T17:56:08.517Z2025-04-06T02:16:59.971ZS-EPMC79698133374677910.3389/fphys.2021.643580