{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Grivas P"],"funding":["Spanish Society of Medical Oncology","American Cancer Society","NCATS NIH HHS","NCI NIH HHS","Prostate Cancer Foundation","NIH"],"pagination":["787-800"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7972830"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["32(6)"],"pubmed_abstract":["<h4>Background</h4>Patients with cancer may be at high risk of adverse outcomes from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We analyzed a cohort of patients with cancer and coronavirus 2019 (COVID-19) reported to the COVID-19 and Cancer Consortium (CCC19) to identify prognostic clinical factors, including laboratory measurements and anticancer therapies.<h4>Patients and methods</h4>Patients with active or historical cancer and a laboratory-confirmed SARS-CoV-2 diagnosis recorded between 17 March and 18 November 2020 were included. The primary outcome was COVID-19 severity measured on an ordinal scale (uncomplicated, hospitalized, admitted to intensive care unit, mechanically ventilated, died within 30 days). Multivariable regression models included demograp"],"journal":["Annals of oncology : official journal of the European Society for Medical Oncology"],"pubmed_title":["Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium."],"pmcid":["PMC7972830"],"funding_grant_id":["T32 CA009515","UL1 TR001873","P30 CA046592","UG1 CA190140","P30 CA056036","P30 CA054174","P30 CA015704","UL1 TR001425","UL1 TR000445","P30 CA168524","P30 CA013696","P30 CA177558","P30 CA046934","P30 CA016058","P30 CA013330","P30 CA196521","UG1 CA189974","P30 CA068485","P30 CA240139","T32 CA236621","U01 CA231840","P30 CA023100","UG1 CA189859"],"pubmed_authors":["Nock NL","Tucker MD","Bernicker EH","Mico V","Rosovsky RP","Schmidt AL","Thompson MA","Fecher LA","Puc M","Dixon B","Peddi P","Salazar M","Zubiri L","Lopes G","Fazio A","Jani C","Menon H","Bakouny Z","Chism DD","Glover MJ","Thakkar A","Huynh-Le M","Wulff-Burchfield E","Bilen MA","Reeves ME","Shah SA","Khaki AR","Desai A","Smits M","Warner JL","Tadesse E","Curran C","Streckfuss M","Shah MR","Gill DM","Lammers PE","Wu JT","Koshkin VS","Bishnoi R","Halfdanarson TR","Li A","Rubinstein SM","Acoba JD","Lyman GH","Gupta S","Hsu E","Farmakiotis D","Wise-Draper TM","Ravindranathan D","Mishra S","Halabi S","Cabal A","Zhu H","Johnson DB","Gulati S","Berg S","Halmos B","Vinh DC","Nagaraj G","Shah DP","Fu J","Mundt D","Yu PP","Stover DG","Grivas P","Kwon DH","Bashir B","Peters S","Piper-Vallillo AJ","Hawley JE","Bouganim N","Shyr Y","Mesa RA","Goyal S","Gadgeel SM","Elkrief A","Rosenstein L","Zhou AY","Patel KG","Bekaii-Saab T","Durbin EB","Shaya JA","Bindal P","Caimi PF","Xie Z","Rivera DR","Schwartz GK","Hennessy C","Stockerl-Goldstein KE","Li X","Friese CR","Doroshow DB","Reuben DY","Verma AK","Park C","Hausrath DJ","McKay RR","Singh SRK","Tachiki L","Nakayama J","Loaiza-Bonilla A","Low CA","Kuderer NM","Hsu CY","Abidi MZ","Painter CA","Nakasone ES","Jayaraj A","Grover P","Weiss M","Lustberg MB","Bowles DW","Kasi A","Crowell J","Subbiah S","Choueiri TK","Galsky MD","Khan H","McNair C","French B","Zhang T","Patel JM","Hwang C","Flora DB","Shah C","Nizam A","Pennell NA","Rini BI"],"additional_accession":[]},"is_claimable":false,"name":"Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium.","description":"<h4>Background</h4>Patients with cancer may be at high risk of adverse outcomes from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We analyzed a cohort of patients with cancer and coronavirus 2019 (COVID-19) reported to the COVID-19 and Cancer Consortium (CCC19) to identify prognostic clinical factors, including laboratory measurements and anticancer therapies.<h4>Patients and methods</h4>Patients with active or historical cancer and a laboratory-confirmed SARS-CoV-2 diagnosis recorded between 17 March and 18 November 2020 were included. The primary outcome was COVID-19 severity measured on an ordinal scale (uncomplicated, hospitalized, admitted to intensive care unit, mechanically ventilated, died within 30 days). Multivariable regression models included demograp","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Jun","modification":"2026-05-01T16:25:25.185Z","creation":"2022-02-11T08:43:49.263Z"},"accession":"S-EPMC7972830","cross_references":{"pubmed":["33746047"],"doi":["10.1016/j.annonc.2021.02.024"]}}