{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Aum S"],"funding":["Korea Institute of Oriental Medicine"],"pagination":["100680"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7972968"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(2)"],"pubmed_abstract":["<h4>Background</h4>Cognitive impairment is an age-dependent chronic disorder that exponentially worsens with age; however, its treatment is mostly symptomatic. Moxibustion is widely accepted in East Asia as a treatment for cognitive impairment. This systematic review aimed to verify the efficacy and underlying mechanism of moxibustion in treating cognitive impairment.<h4>Methods</h4>Sixteen trials involving 324 animals obtained from MEDLINE (PubMed), EMBASE, the Cochrane library, the Chinese National Knowledge Infrastructure, Wan-Fang, Cqvip, the Korean Studies Information Service System, and the Oriental Medicine Advanced Searching Integrated System met the inclusion criteria. We extracted the results of behavioral tests and immunohistochemical biomarkers from the included articles and ev"],"journal":["Integrative medicine research"],"pubmed_title":["Moxibustion for cognitive impairment: a systematic review and meta-analysis of animal studies."],"pmcid":["PMC7972968"],"funding_grant_id":["KSN1621051"],"pubmed_authors":["Cai M","Aum S","Jerng UM","Choe S","Lee JH"],"additional_accession":[]},"is_claimable":false,"name":"Moxibustion for cognitive impairment: a systematic review and meta-analysis of animal studies.","description":"<h4>Background</h4>Cognitive impairment is an age-dependent chronic disorder that exponentially worsens with age; however, its treatment is mostly symptomatic. Moxibustion is widely accepted in East Asia as a treatment for cognitive impairment. This systematic review aimed to verify the efficacy and underlying mechanism of moxibustion in treating cognitive impairment.<h4>Methods</h4>Sixteen trials involving 324 animals obtained from MEDLINE (PubMed), EMBASE, the Cochrane library, the Chinese National Knowledge Infrastructure, Wan-Fang, Cqvip, the Korean Studies Information Service System, and the Oriental Medicine Advanced Searching Integrated System met the inclusion criteria. We extracted the results of behavioral tests and immunohistochemical biomarkers from the included articles and ev","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Jun","modification":"2025-04-22T08:21:21.078Z","creation":"2025-04-05T22:29:14.328Z"},"accession":"S-EPMC7972968","cross_references":{"pubmed":["33747784"],"doi":["10.1016/j.imr.2020.100680"]}}