biostudies-literatureUnknown91(7-S)Luzzi S<h4>Background</h4>Adoptive immunotherapies are among the pillars of ongoing biological breakthroughs in neuro-oncology, as their potential applications are tremendously wide. The present literature review comprehensively classified adoptive immunotherapies in neuro-oncology, provides an update, and overviews the main translational challenges of this approach.<h4>Methods</h4>The PubMed/MEDLINE platform, Medical Subject Heading (MeSH) database, and ClinicalTrials.gov website were the sources. The MeSH terms "Immunotherapy, Adoptive," "Cell- and Tissue-Based Therapy," "Tissue Engineering," and "Cell Engineering" were combined with "Central Nervous System," and "Brain." "Brain tumors" and "adoptive immunotherapy" were used for a further unrestricted search. Only articles published in the lastActa bio-medica : Atenei Parmensis18-31https://www.ebi.ac.uk/biostudies/studies/S-EPMC7975830biostudies-literatureAdoptive immunotherapies in neuro-oncology: classification, recent advances, and translational challenges.PMC7975830Magistrali MLuzzi SMosconi MSavasta SGiotta Lucifero AFoiadelli TBrambilla IfalseAdoptive immunotherapies in neuro-oncology: classification, recent advances, and translational challenges.<h4>Background</h4>Adoptive immunotherapies are among the pillars of ongoing biological breakthroughs in neuro-oncology, as their potential applications are tremendously wide. The present literature review comprehensively classified adoptive immunotherapies in neuro-oncology, provides an update, and overviews the main translational challenges of this approach.<h4>Methods</h4>The PubMed/MEDLINE platform, Medical Subject Heading (MeSH) database, and ClinicalTrials.gov website were the sources. The MeSH terms "Immunotherapy, Adoptive," "Cell- and Tissue-Based Therapy," "Tissue Engineering," and "Cell Engineering" were combined with "Central Nervous System," and "Brain." "Brain tumors" and "adoptive immunotherapy" were used for a further unrestricted search. Only articles published in the last2020-01-01T00:00:00Z2020 Jun2025-04-04T08:27:45.162Z2025-04-04T08:27:45.162ZS-EPMC79758303260837310.23750/abm.v91i7-S.9952