{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["David SG"],"funding":["Instituto Nacional de Ciência e Tecnologia para Excitotoxicidade e Neuroproteção","Conselho Nacional de Desenvolvimento Científico e Tecnológico","FIC NIH HHS","Fogarty International Center","Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro"],"pagination":["150-155"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7978502"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["59"],"pubmed_abstract":["<h4>Objectives</h4>The diagnosis of pediatric tuberculosis (TB) presents many challenges, and is further complicated in HIV-infected patients. While many diagnostic systems have been proposed, there is no pediatric TB diagnosis gold standard. The outcomes of four TB diagnostic systems in HIV-infected children were compared in this study.<h4>Methods</h4>A retrospective cohort study was conducted at a TB/HIV reference hospital in Rio de Janeiro. HIV-infected pediatric patients evaluated for TB from 1998 to 2010 were reassessed using four diagnostic systems: Kenneth Jones, 1969; Tidjani, 1986; Ben Marais, 2006; Brazilian Ministry of Health, 2010. Results were compared to standardized diagnoses made by an expert panel of physicians.<h4>Results</h4>Of the 121 patients in the study cohort, the e"],"journal":["International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases"],"pubmed_title":["A comparison of tuberculosis diagnostic systems in a retrospective cohort of HIV-infected children in Rio de Janeiro, Brazil."],"pmcid":["PMC7978502"],"funding_grant_id":["R25 TW009338","305044/2012-5","D43 TW010540","573548/2008-0","25TW009338"],"pubmed_authors":["Kritski AL","Pombo March MFB","Lovero KL","Ruffino Netto A","David SG","Abreu TG","Sant'Anna CC","Rede-TB Study Group"],"additional_accession":[]},"is_claimable":false,"name":"A comparison of tuberculosis diagnostic systems in a retrospective cohort of HIV-infected children in Rio de Janeiro, Brazil.","description":"<h4>Objectives</h4>The diagnosis of pediatric tuberculosis (TB) presents many challenges, and is further complicated in HIV-infected patients. While many diagnostic systems have been proposed, there is no pediatric TB diagnosis gold standard. The outcomes of four TB diagnostic systems in HIV-infected children were compared in this study.<h4>Methods</h4>A retrospective cohort study was conducted at a TB/HIV reference hospital in Rio de Janeiro. HIV-infected pediatric patients evaluated for TB from 1998 to 2010 were reassessed using four diagnostic systems: Kenneth Jones, 1969; Tidjani, 1986; Ben Marais, 2006; Brazilian Ministry of Health, 2010. Results were compared to standardized diagnoses made by an expert panel of physicians.<h4>Results</h4>Of the 121 patients in the study cohort, the e","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Jun","modification":"2025-04-18T13:29:05.453Z","creation":"2025-04-06T23:16:14.016Z"},"accession":"S-EPMC7978502","cross_references":{"pubmed":["28455104"],"doi":["10.1016/j.ijid.2017.01.038"]}}