biostudies-literatureDavid SGInstituto Nacional de Ciência e Tecnologia para Excitotoxicidade e NeuroproteçãoConselho Nacional de Desenvolvimento Científico e TecnológicoFIC NIH HHSFogarty International CenterFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro150-155https://www.ebi.ac.uk/biostudies/studies/S-EPMC7978502biostudies-literatureUnknown59<h4>Objectives</h4>The diagnosis of pediatric tuberculosis (TB) presents many challenges, and is further complicated in HIV-infected patients. While many diagnostic systems have been proposed, there is no pediatric TB diagnosis gold standard. The outcomes of four TB diagnostic systems in HIV-infected children were compared in this study.<h4>Methods</h4>A retrospective cohort study was conducted at a TB/HIV reference hospital in Rio de Janeiro. HIV-infected pediatric patients evaluated for TB from 1998 to 2010 were reassessed using four diagnostic systems: Kenneth Jones, 1969; Tidjani, 1986; Ben Marais, 2006; Brazilian Ministry of Health, 2010. Results were compared to standardized diagnoses made by an expert panel of physicians.<h4>Results</h4>Of the 121 patients in the study cohort, the eInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious DiseasesA comparison of tuberculosis diagnostic systems in a retrospective cohort of HIV-infected children in Rio de Janeiro, Brazil.PMC7978502R25 TW009338305044/2012-5D43 TW010540573548/2008-025TW009338Kritski ALPombo March MFBLovero KLRuffino Netto ADavid SGAbreu TGSant'Anna CCRede-TB Study GroupfalseA comparison of tuberculosis diagnostic systems in a retrospective cohort of HIV-infected children in Rio de Janeiro, Brazil.<h4>Objectives</h4>The diagnosis of pediatric tuberculosis (TB) presents many challenges, and is further complicated in HIV-infected patients. While many diagnostic systems have been proposed, there is no pediatric TB diagnosis gold standard. The outcomes of four TB diagnostic systems in HIV-infected children were compared in this study.<h4>Methods</h4>A retrospective cohort study was conducted at a TB/HIV reference hospital in Rio de Janeiro. HIV-infected pediatric patients evaluated for TB from 1998 to 2010 were reassessed using four diagnostic systems: Kenneth Jones, 1969; Tidjani, 1986; Ben Marais, 2006; Brazilian Ministry of Health, 2010. Results were compared to standardized diagnoses made by an expert panel of physicians.<h4>Results</h4>Of the 121 patients in the study cohort, the e2017-01-01T00:00:00Z2017 Jun2025-04-18T13:29:05.453Z2025-04-06T23:16:14.016ZS-EPMC79785022845510410.1016/j.ijid.2017.01.038