{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hinkle JT"],"funding":["National Institute of Neurological Disorders and Stroke","NCATS NIH HHS","NIA NIH HHS","NINDS NIH HHS","National Institute of General Medical Sciences","NIGMS NIH HHS","National Institute on Aging"],"pagination":["23-28"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7980283"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["84"],"pubmed_abstract":["<h4>Background</h4>Punding is a complication of Parkinson's disease (PD) treatment and stimulant abuse that features excessive preoccupation with repetitive and/or aimless behaviors. We hypothesized that cognitive impairment and functional limitations influence how punding behaviors manifest in PD.<h4>Methods</h4>We extracted data on punding, hobbyism, and cognition from the Parkinson's Progression Marker Initiative (PPMI). Punding and hobbyism were measured with the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease (QUIP) scale. We determined how cognition predicted punding and hobbyism behaviors-adjusting for levodopa dose, Hoehn & Yahr stage, disease duration, and age-using generalized estimating equation (GEE) logistic regression. Activities of daily living (ADL) "],"journal":["Parkinsonism & related disorders"],"pubmed_title":["Attentional dysfunction and the punding spectrum in Parkinson's disease."],"pmcid":["PMC7980283"],"funding_grant_id":["KL2 TR001077","K23 AG044441","T32 GM007309","K23 NS101096","T32 GM136577","F30 AG067643"],"pubmed_authors":["Perepezko K","Mills KA","Hinkle JT","Pontone GM"],"additional_accession":[]},"is_claimable":false,"name":"Attentional dysfunction and the punding spectrum in Parkinson's disease.","description":"<h4>Background</h4>Punding is a complication of Parkinson's disease (PD) treatment and stimulant abuse that features excessive preoccupation with repetitive and/or aimless behaviors. We hypothesized that cognitive impairment and functional limitations influence how punding behaviors manifest in PD.<h4>Methods</h4>We extracted data on punding, hobbyism, and cognition from the Parkinson's Progression Marker Initiative (PPMI). Punding and hobbyism were measured with the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease (QUIP) scale. We determined how cognition predicted punding and hobbyism behaviors-adjusting for levodopa dose, Hoehn & Yahr stage, disease duration, and age-using generalized estimating equation (GEE) logistic regression. Activities of daily living (ADL) ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Mar","modification":"2025-04-04T19:54:21.09Z","creation":"2025-04-04T19:54:21.09Z"},"accession":"S-EPMC7980283","cross_references":{"pubmed":["33545553"],"doi":["10.1016/j.parkreldis.2021.01.019"]}}