biostudies-literatureHinkle JTNational Institute of Neurological Disorders and StrokeNCATS NIH HHSNIA NIH HHSNINDS NIH HHSNational Institute of General Medical SciencesNIGMS NIH HHSNational Institute on Aging23-28https://www.ebi.ac.uk/biostudies/studies/S-EPMC7980283biostudies-literatureUnknown84<h4>Background</h4>Punding is a complication of Parkinson's disease (PD) treatment and stimulant abuse that features excessive preoccupation with repetitive and/or aimless behaviors. We hypothesized that cognitive impairment and functional limitations influence how punding behaviors manifest in PD.<h4>Methods</h4>We extracted data on punding, hobbyism, and cognition from the Parkinson's Progression Marker Initiative (PPMI). Punding and hobbyism were measured with the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease (QUIP) scale. We determined how cognition predicted punding and hobbyism behaviors-adjusting for levodopa dose, Hoehn & Yahr stage, disease duration, and age-using generalized estimating equation (GEE) logistic regression. Activities of daily living (ADL) Parkinsonism & related disordersAttentional dysfunction and the punding spectrum in Parkinson's disease.PMC7980283KL2 TR001077K23 AG044441T32 GM007309K23 NS101096T32 GM136577F30 AG067643Perepezko KMills KAHinkle JTPontone GMfalseAttentional dysfunction and the punding spectrum in Parkinson's disease.<h4>Background</h4>Punding is a complication of Parkinson's disease (PD) treatment and stimulant abuse that features excessive preoccupation with repetitive and/or aimless behaviors. We hypothesized that cognitive impairment and functional limitations influence how punding behaviors manifest in PD.<h4>Methods</h4>We extracted data on punding, hobbyism, and cognition from the Parkinson's Progression Marker Initiative (PPMI). Punding and hobbyism were measured with the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease (QUIP) scale. We determined how cognition predicted punding and hobbyism behaviors-adjusting for levodopa dose, Hoehn & Yahr stage, disease duration, and age-using generalized estimating equation (GEE) logistic regression. Activities of daily living (ADL) 2021-01-01T00:00:00Z2021 Mar2025-04-04T19:54:21.09Z2025-04-04T19:54:21.09ZS-EPMC79802833354555310.1016/j.parkreldis.2021.01.019