{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chroumpi T"],"funding":["Academy of Finland","Dutch Research Council (NWO)"],"pagination":["644216"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7982397"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9"],"pubmed_abstract":["The filamentous ascomycete <i>Aspergillus niger</i> has received increasing interest as a cell factory, being able to efficiently degrade plant cell wall polysaccharides as well as having an extensive metabolism to convert the released monosaccharides into value added compounds. The pentoses D-xylose and L-arabinose are the most abundant monosaccharides in plant biomass after the hexose D-glucose, being major constituents of xylan, pectin and xyloglucan. In this study, the influence of selected pentose catabolic pathway (PCP) deletion strains on growth on plant biomass and re-routing of sugar catabolism was addressed to gain a better understanding of the flexibility of this fungus in using plant biomass-derived monomers. The transcriptome, metabolome and proteome response of three PCP muta"],"journal":["Frontiers in bioengineering and biotechnology"],"pubmed_title":["Re-routing of Sugar Catabolism Provides a Better Insight Into Fungal Flexibility in Using Plant Biomass-Derived Monomers as Substrates."],"pmcid":["PMC7982397"],"funding_grant_id":["ALWOP.233"],"pubmed_authors":["Tolic N","Clendinen CS","Markillie LM","Mitchell HD","Nicora CD","Orr G","Makela MR","de Vries RP","Paurus V","Chroumpi T","Peng M","Hutchinson CM","Baker SE"],"additional_accession":[]},"is_claimable":false,"name":"Re-routing of Sugar Catabolism Provides a Better Insight Into Fungal Flexibility in Using Plant Biomass-Derived Monomers as Substrates.","description":"The filamentous ascomycete <i>Aspergillus niger</i> has received increasing interest as a cell factory, being able to efficiently degrade plant cell wall polysaccharides as well as having an extensive metabolism to convert the released monosaccharides into value added compounds. The pentoses D-xylose and L-arabinose are the most abundant monosaccharides in plant biomass after the hexose D-glucose, being major constituents of xylan, pectin and xyloglucan. In this study, the influence of selected pentose catabolic pathway (PCP) deletion strains on growth on plant biomass and re-routing of sugar catabolism was addressed to gain a better understanding of the flexibility of this fungus in using plant biomass-derived monomers. The transcriptome, metabolome and proteome response of three PCP muta","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2026-04-07T19:24:10.569Z","creation":"2024-11-13T06:29:37.735Z"},"accession":"S-EPMC7982397","cross_references":{"pubmed":["33763411"],"doi":["10.3389/fbioe.2021.644216"]}}