biostudies-literatureUnknown69(3)Andrew MKPublic Health Agency of CanadaGlaxoSmithKlineCIHR<h4>Background/objectives</h4>Influenza is associated with significant morbidity and mortality, particularly for older adults. Persistent functional decline following hospitalization has important impacts on older adults' wellbeing and independence, but has been under-studied in relation to influenza. We aimed to investigate persistent functional change in older adults admitted to hospital with influenza and other acute respiratory illness (ARI).<h4>Design</h4>Protective observational cohort study.<h4>Setting</h4>Canadian Immunization Research Network Serious Outcomes Surveillance Network 2011 to 2012 influenza season.<h4>Participants</h4>A total of 925 patients aged 65 and older admitted to hospital with influenza and other ARI.<h4>Measurements</h4>Influenza was laboratory-confirmed. FraiJournal of the American Geriatrics Society696-703https://www.ebi.ac.uk/biostudies/studies/S-EPMC7984066biostudies-literaturePersistent Functional Decline Following Hospitalization with Influenza or Acute Respiratory Illness.PMC7984066McElhaney JELeBlanc JMcGeer AMcNeil SAGodin JHatchette TFMacDonald SBowie WSemret MAndrew MKKatz KfalsePersistent Functional Decline Following Hospitalization with Influenza or Acute Respiratory Illness.<h4>Background/objectives</h4>Influenza is associated with significant morbidity and mortality, particularly for older adults. Persistent functional decline following hospitalization has important impacts on older adults' wellbeing and independence, but has been under-studied in relation to influenza. We aimed to investigate persistent functional change in older adults admitted to hospital with influenza and other acute respiratory illness (ARI).<h4>Design</h4>Protective observational cohort study.<h4>Setting</h4>Canadian Immunization Research Network Serious Outcomes Surveillance Network 2011 to 2012 influenza season.<h4>Participants</h4>A total of 925 patients aged 65 and older admitted to hospital with influenza and other ARI.<h4>Measurements</h4>Influenza was laboratory-confirmed. Frai2021-01-01T00:00:00Z2021 Mar2025-04-22T02:06:19.808Z2025-04-05T20:15:23.168ZS-EPMC79840663329498610.1111/jgs.16950