biostudies-literatureUnknown22(3)Teruel JRThe purpose of this work is to establish an automated approach for a multiple isocenter volumetric arc therapy (VMAT)-based TBI treatment planning approach. Five anonymized full-body CT imaging sets were used. A script was developed to automate and standardize the treatment planning process using the Varian Eclipse v15.6 Scripting API. The script generates two treatment plans: a head-first VMAT-based plan for upper body coverage using four isocenters and a total of eight full arcs; and a feet-first AP/PA plan with three isocenters that covers the lower extremities of the patient. PTV was the entire body cropped 5 mm from the patient surface and extended 3 mm into the lungs and kidneys. Two plans were generated for each case: one to a total dose of 1200 cGy in 8 fractions and a second one tJournal of applied clinical medical physics119-130https://www.ebi.ac.uk/biostudies/studies/S-EPMC7984467biostudies-literatureAutomatic treatment planning for VMAT-based total body irradiation using Eclipse scripting.PMC7984467Osterman KSHitchen CMalin MTeruel JRGalavis PEGerber NKTaneja SBarbee DLMcCarthy AfalseAutomatic treatment planning for VMAT-based total body irradiation using Eclipse scripting.The purpose of this work is to establish an automated approach for a multiple isocenter volumetric arc therapy (VMAT)-based TBI treatment planning approach. Five anonymized full-body CT imaging sets were used. A script was developed to automate and standardize the treatment planning process using the Varian Eclipse v15.6 Scripting API. The script generates two treatment plans: a head-first VMAT-based plan for upper body coverage using four isocenters and a total of eight full arcs; and a feet-first AP/PA plan with three isocenters that covers the lower extremities of the patient. PTV was the entire body cropped 5 mm from the patient surface and extended 3 mm into the lungs and kidneys. Two plans were generated for each case: one to a total dose of 1200 cGy in 8 fractions and a second one t2021-01-01T00:00:00Z2021 Mar2025-04-05T15:24:41.344Z2025-04-05T15:24:41.344ZS-EPMC79844673356521410.1002/acm2.13189