{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rysavy MA"],"funding":["U.S. Department of Health &amp; Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","NICHD NIH HHS","NCATS NIH HHS","U.S. Department of Health &amp; Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development"],"pagination":["2270-2278"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7985590"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["41(9)"],"pubmed_abstract":["<h4>Objective</h4>Determine how neurodevelopmental impairment (NDI) relates to concurrent outcomes for children born extremely preterm.<h4>Study design</h4>Retrospective cohort study children born 22 0/7-26 6/7 weeks' gestation at NICHD Neonatal Research Network hospitals. Outcomes were ascertained at 18-22 months' corrected age.<h4>Result</h4>Of 6562 children, 2618 (40%) died and 441 (7%) had no follow-up. Among the remaining 3483 children, 825 (24%), 1576 (45%), 657 (19%), and 425 (12%) had no, potential/mild, moderate, and severe NDI, respectively. Rehospitalization, respiratory medications, surgery, and medical support services were associated with greater NDI severity but affected >10% of children without NDI. Rehospitalization occurred in 40% of children with no NDI (mean (SD): 1.7 ("],"journal":["Journal of perinatology : official journal of the California Perinatal Association"],"pubmed_title":["The relationship of neurodevelopmental impairment to concurrent early childhood outcomes of extremely preterm infants."],"pmcid":["PMC7985590"],"funding_grant_id":["UG1 HD027904","U10 HD53109","U10HD68244","U10HD27880","U10HD34216","U10 HD027904","UL1 TR003167","U10 HD053109","F32HD098782","U24 HD095254","UG1 HD087226","U10HD53109"],"pubmed_authors":["Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network","Colaizy TT","Johnson KJ","Vohr BR","Brumbaugh JE","Bell EF","Bann CM","DeMauro SB","Duncan AF","Peralta-Carcelen M","Harmon HM","Rysavy MA","Hintz SR"],"additional_accession":[]},"is_claimable":false,"name":"The relationship of neurodevelopmental impairment to concurrent early childhood outcomes of extremely preterm infants.","description":"<h4>Objective</h4>Determine how neurodevelopmental impairment (NDI) relates to concurrent outcomes for children born extremely preterm.<h4>Study design</h4>Retrospective cohort study children born 22 0/7-26 6/7 weeks' gestation at NICHD Neonatal Research Network hospitals. Outcomes were ascertained at 18-22 months' corrected age.<h4>Result</h4>Of 6562 children, 2618 (40%) died and 441 (7%) had no follow-up. Among the remaining 3483 children, 825 (24%), 1576 (45%), 657 (19%), and 425 (12%) had no, potential/mild, moderate, and severe NDI, respectively. Rehospitalization, respiratory medications, surgery, and medical support services were associated with greater NDI severity but affected >10% of children without NDI. Rehospitalization occurred in 40% of children with no NDI (mean (SD): 1.7 (","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2025-04-21T23:38:11.178Z","creation":"2025-04-05T19:12:55.182Z"},"accession":"S-EPMC7985590","cross_references":{"pubmed":["33758389"],"doi":["10.1038/s41372-021-00999-7"]}}