{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Skocek O"],"funding":["NICHD NIH HHS"],"pagination":["429-432"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7990085"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(6)"],"pubmed_abstract":["Thus far, optical recording of neuronal activity in freely behaving animals has been limited to a thin axial range. We present a head-mounted miniaturized light-field microscope (MiniLFM) capable of capturing neuronal network activity within a volume of 700 × 600 × 360 µm<sup>3</sup> at 16 Hz in the hippocampus of freely moving mice. We demonstrate that neurons separated by as little as ~15 µm and at depths up to 360 µm can be discriminated."],"journal":["Nature methods"],"pubmed_title":["High-speed volumetric imaging of neuronal activity in freely moving rodents."],"pmcid":["PMC7990085"],"funding_grant_id":["U54 HD087101"],"pubmed_authors":["Martinez Traub F","Nobauer T","Yamagata M","Cox DD","Xia CN","Grama A","Skocek O","Aharoni D","Golshani P","Weilguny L","Molodtsov MI","Vaziri A"],"additional_accession":[]},"is_claimable":false,"name":"High-speed volumetric imaging of neuronal activity in freely moving rodents.","description":"Thus far, optical recording of neuronal activity in freely behaving animals has been limited to a thin axial range. We present a head-mounted miniaturized light-field microscope (MiniLFM) capable of capturing neuronal network activity within a volume of 700 × 600 × 360 µm<sup>3</sup> at 16 Hz in the hippocampus of freely moving mice. We demonstrate that neurons separated by as little as ~15 µm and at depths up to 360 µm can be discriminated.","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Jun","modification":"2025-04-04T12:32:36.097Z","creation":"2025-02-18T23:35:57.842Z"},"accession":"S-EPMC7990085","cross_references":{"pubmed":["29736000"],"doi":["10.1038/s41592-018-0008-0"]}}